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Creatine для Mental Fatigue

B

A systematic review found moderate certainty evidence for positive effects on memory and processing speed. Single-dose supplementation improved cognitive performance during sleep deprivation through ATP replenishment.

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B

Итог

A systematic review found moderate certainty evidence for positive effects on memory and processing speed. Single-dose supplementation improved cognitive performance during sleep deprivation through ATP replenishment.

Key Study Findings

Review
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?
Dose: None или: None Outcome: None Эффект: None None

Популяция: narrative review of creatine supplementation effects on brain function

Other 24 weeks
Analysis of Incidence and Clinical Characteristics of RSV Infection in Hospitalized Children: A Retrospective Study.
Dose: 71.9% или: None Outcome: None Эффект: None None

Популяция: rsv infection from january 2019 to december 2020

Randomized Controlled Trial Double-blind
Can Creatine Combat the Mental Fatigue-associated Decrease in Visuomotor Skills?
Dose: 20 g или: placebo Outcome: throughout the protocol Эффект: None P = 0.022

Популяция: healthy participants

Review
Beyond sports: Efficacy and safety of creatine supplementation in pathological or paraphysiological conditions of brain …
Dose: 20 g/d или: Placebo Outcome: None Эффект: None None

Популяция: elderly

Cohort Study n=480
Decrease in Serum Vitamin D Level of Older Patients with Fatigue.
Dose: None или: Control Outcome: Cognitive function Эффект: None p=0.05

Популяция: patients with fatigue and 240 controls without fatigue,

Systematic Review n=281
Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized …
Dose: None или: None Outcome: Cognitive function (memory, intelligence/reasoning) Эффект: None None

Популяция: Healthy individuals

Key Statistics

8

Исследования

600

Участники

Positive

B

Оценка

Referenced Papers

Medicine and science … 2020 63 цитирований
Nutrients 2019 23 цитирований
Polish archives of … 2017 95 цитирований
Nutrition (Burbank, Los … 2009 85 цитирований
Neuroscience research 2002 180 цитирований
Pharmacology, biochemistry, and … 1998 60 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
3-5 g/day creatine monohydrate
cognitivesupport:
5 g/day

Верхний предел: 5 g/day considered safe for long-term use (ISSN position)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Mixed --
71.9% 24 weeks Positive --
20 g -- Positive --
20 g/d -- Positive --
None -- Mixed 480
None -- Positive 281
None -- Positive 16
None -- Positive --

Лучшее время приёма: Any time of day; with or without food

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Water retention
  • Mild gastrointestinal discomfort
  • Weight gain (water weight)
  • Muscle cramping (rare, dose-dependent)

Известные взаимодействия

  • Nephrotoxic drugs (monitor kidney function with concurrent use)
  • Caffeine (may partially attenuate creatine loading, debated)
  • NSAIDs (theoretical additive kidney stress at high doses)

Допустимый верхний уровень потребления: 5 g/day considered safe for long-term use (ISSN position)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Creatine help with Mental Fatigue?
Based on 8 studies with 600 participants, there is moderate evidence from clinical studies that Creatine may support Mental Fatigue management. Our evidence grade is B (Good Evidence).
How much Creatine should I take for Mental Fatigue?
Studies have used various dosages. A commonly studied range is 3-5 g/day creatine monohydrate. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Creatine?
Reported side effects may include Water retention, Mild gastrointestinal discomfort, Weight gain (water weight), Muscle cramping (rare, dose-dependent). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Creatine and Mental Fatigue?
We rate the evidence as Grade B (Good Evidence). This rating is based on 8 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Mental Fatigue

Creatine для других состояний

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