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Molecular pathways through which resveratrol and related polyphenols may attenuate mitochondrial oxidative damage in aging neurons. The schematic outlines receptor interactions, gene expression modulation, and downstream effects on cellular energy metabolism.

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![Figure 6: Molecular pathways through which resveratrol and related polyphenols may attenuate mitochondrial oxidative damage in aging neurons. The schematic outlines receptor interactions, gene expression modulation, and downstream effects on cellular energy metabolism.]()

> Source: Imane Lejri et al. "Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Rel." *Oxidative medicine and cellular longevity*, 2019. PMID: [31214285](https://pubmed.ncbi.nlm.nih.gov/31214285/)
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  <img src="" alt="Molecular pathways through which resveratrol and related polyphenols may attenuate mitochondrial oxidative damage in aging neurons. The schematic outlines receptor interactions, gene expression modulation, and downstream effects on cellular energy metabolism." />
  <figcaption>Figure 6. Molecular pathways through which resveratrol and related polyphenols may attenuate mitochondrial oxidative damage in aging neurons. The schematic outlines receptor interactions, gene expression modulation, and downstream effects on cellular energy metabolism.<br>  Source: Imane Lejri et al. "Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Rel." <em>Oxidative medicine and cellular longevity</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31214285/">31214285</a></figcaption>
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