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Melatonin has multiorgan effects.

Lionel H Opie, Sandrine Lecour
Review European heart journal. Cardiovascular pharmacotherapy 2016 77 次引用
PubMed DOI
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Study Design

研究类型
Review
研究人群
General population (melatonin multiorgan effects)
干预措施
Melatonin has multiorgan effects. None
对照组
None
主要结局
None
效应方向
Mixed
偏倚风险
Unclear

Abstract

Melatonin, widely used to counter transatlantic travel jet lag and insomnia, is synthesized in the suprachiasmatic nucleus of the anterior pituitary gland. Its release into the circulation is stimulated by the onset of darkness, followed by a progressive decrease in blood levels with the onset of dawn. Melatonin administration can maintain the quality of sleep and help to counteract age-induced cognitive decline. Melatonin can also limit the severity of a variety of cardiovascular and cerebrovascular diseases, diabetes, and cancer.

简要概述

Melatonin administration can maintain the quality of sleep and help to counteract age-induced cognitive decline, and limit the severity of a variety of cardiovascular and cerebrovascular diseases, diabetes, and cancer.

Used In Evidence Reviews

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