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BrainCited

Forschungsprozess

368 Abbildungen aus begutachteter Forschung

Alle Vitamin E Green Tea Extract (EGCG) Citicoline Folate Zinc Bacopa monnieri Omega-3 Fatty Acids (DHA/EPA) Alpha-Lipoic Acid Creatine Resveratrol Vitamin D L-Theanine Vitamin B12 Ginkgo biloba Lutein & Zeaxanthin Melatonin Rhodiola rosea Panax Ginseng Phosphatidylserine Taurine Curcumin Uridine Monophosphate
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Figure 9
Figure 9 Chart

Heatmap of top differentially abundant metabolites clusters precocious and normal crabs into distinct groups based on metabolic signatures.

Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old …

Figure 11
Figure 11 Chart

Lipid metabolite classes are quantified across crab groups, showing elevated steroid and fatty acid metabolites associated with the precocious phenotype.

Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old …

Figure 13
Figure 13 Diagram

Integrated pathway visualization connects transcriptomic gene expression changes to metabolomic shifts in the phenylalanine metabolism pathway of precocious crabs.

Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old …

Figure 15
Figure 15 Chart

Quantitative PCR validation confirms the differential expression of selected genes identified in the transcriptomic analysis between precocious and normal crabs.

Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old …

The phenylalanine metabolism (a) and neuroactive ligand-receptor interaction (b) KEGG pathway. Red indicates up-regulation; green indicates down-regulation.
Figure 17 Diagram

KEGG pathway maps for phenylalanine metabolism and neuroactive ligand-receptor interaction show up- and down-regulated components in precocious crabs, with red indicating increased expression.

Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old …

Figure 18
Figure 18 Chart

Supplementary integrated analysis data provides additional support for the multi-omics characterization of precocious development in Eriocheir sinensis.

Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old …

Figure 6
Figure 6 Chart

Blood levels of DHA, EPA, and arachidonic acid are tracked over the intervention period, confirming adherence and bioavailability of the fatty acid supplement.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 7
Figure 7 Chart

Plasma lutein and zeaxanthin concentrations are compared between treatment and control groups, demonstrating successful supplementation and absorption.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 8
Figure 8 Chart

Macular pigment optical density measurements assess the accumulation of lutein and zeaxanthin in the retina following supplementation.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 9
Figure 9 Chart

Verbal memory test performance including word recall and recognition tasks is compared between supplementation and placebo groups.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 10
Figure 10 Chart

Visual memory and spatial recall scores are assessed following LCPUFA and lutein/zeaxanthin supplementation compared to placebo.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 11
Figure 11 Chart

Working memory and executive function task results are presented for both treatment arms, assessing broader cognitive effects of the combined supplementation.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 12
Figure 12 Chart

Processing speed assessments compare reaction time and cognitive throughput between the supplemented and placebo groups.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 13
Figure 13 Chart

Subgroup analyses stratify cognitive outcomes by baseline DHA status, revealing whether individuals with lower initial omega-3 levels benefit more from supplementation.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 14
Figure 14 Chart

Adverse event reporting and safety data demonstrate the tolerability of combined LCPUFA and carotenoid supplementation in older adults.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 15
Figure 15 Chart

Correlation analysis between blood fatty acid levels and episodic memory improvements explores dose-response relationships in the supplementation trial.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 16
Figure 16 Chart

Additional cognitive domain scores including attention and language fluency are compared between groups as secondary outcome measures.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 5. Combined analysis of the changes (∆-adjusted) in the scores of episodic memory function tests for subgroups with cognitive decline in Trials 1 and 2. (A) composite memory; (B), verbal memory; (C), visual memory. LCPUFAs, long-chain polyunsaturat
Figure 17 Chart

Combined analysis of episodic memory score changes in subgroups with low versus adequate baseline omega-3 status indicates differential treatment responses to LCPUFA supplementation with lutein and zeaxanthin.

Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin …

Figure 2
Figure 2 Forest Plot

Forest plot of randomized controlled trials evaluates the pooled effect of omega-3, DHA, and EPA supplementation on cognitive function scores in Alzheimer's disease patients.

The effects of omega-3, DHA, EPA, Souvenaid® in Alzheimer's disease: A systematic …

Figure 3
Figure 3 Forest Plot

Subgroup analysis by intervention type separates the effects of pure omega-3 supplements from the multinutrient Souvenaid formulation on Alzheimer's disease outcomes.

The effects of omega-3, DHA, EPA, Souvenaid® in Alzheimer's disease: A systematic …

Figure 4
Figure 4 Forest Plot

Forest plot assessing the impact of omega-3 supplementation on functional daily living activities in Alzheimer's disease patients across included trials.

The effects of omega-3, DHA, EPA, Souvenaid® in Alzheimer's disease: A systematic …

Figure 5
Figure 5 Chart

Risk of bias assessment for included studies is visualized using the Cochrane tool, indicating overall moderate quality of evidence across the meta-analysis.

The effects of omega-3, DHA, EPA, Souvenaid® in Alzheimer's disease: A systematic …

Figure 6
Figure 6 Chart

Funnel plot analysis evaluates publication bias across the studies included in the systematic review of omega-3 fatty acids for Alzheimer's disease.

The effects of omega-3, DHA, EPA, Souvenaid® in Alzheimer's disease: A systematic …

Fig. 1 PRISMA flowchart of all included studies
Figure 2

Fig. 1 PRISMA flowchart of all included studies

The effects of L-theanine supplementation on the outcomes of patients with mental …

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