Basado en evidencia Revisiones de suplementos
Every brain claim cited.
We read the cognitive health studies so you don't have to.
Evidence-based supplement research you can trust. We analyze peer-reviewed clinical studies from PubMed and grade every supplement ingredient on a transparent A–D scale. No sponsored rankings, no manufacturer influence — just science.
Featured Ingredients
Citicoline
nootropicDonates choline for acetylcholine synthesis and cytidine for uridine production; supports phosphatidylcholine synthesis essential for neuronal membrane repair and integrity; …
Lion's Mane Mushroom
mushroomContains bioactive hericenones and erinacines that stimulate nerve growth factor (NGF) synthesis; promotes neurogenesis and myelination; supports hippocampal function and …
Phosphatidylserine
nootropicEssential phospholipid component of neuronal cell membranes; supports cell-to-cell communication, neurotransmitter release (acetylcholine, dopamine), and cortisol regulation; maintains membrane fluidity …
Curcumin
antioxidantCrosses the blood-brain barrier in enhanced forms; binds to amyloid-beta plaques reducing aggregation; reduces tau phosphorylation; exhibits potent anti-neuroinflammatory effects; …
Magnesium L-Threonate
mineralThe only magnesium form demonstrated to effectively cross the blood-brain barrier; increases synaptic density in hippocampal and prefrontal regions; enhances …
Omega-3 Fatty Acids (DHA/EPA)
fatty_acidSupports neuronal membrane integrity and fluidity; DHA constitutes approximately 40% of polyunsaturated fatty acids in the brain, supporting synaptic function, …
Top Conditions
Age-Related Cognitive Decline
Affects virtually all adults to some degree after age 50
Brain Fog
Reported by 20-30% of the general population
Attention & Focus Difficulties
Among the most reported cognitive complaints across all age groups
Mental Fatigue
Highly prevalent in modern knowledge-work environments
Sleep-Related Cognitive Impairment
35% of adults sleep less than 7 hours; 50-70 million have sleep disorders
Oxidative Stress & Neuroinflammation
Universal process that accelerates with age and environmental exposure
Recent Evidence Updates
10 estudios
8 estudios
12 estudios
6 estudios
10 estudios
Popular Comparisons
Latest Research
J Sleep Res · 2017
European guideline for the diagnosis and treatment of insomnia.
Pflugers Arch · 2010
Glutamate receptors, neurotoxicity and neurodegeneration.
Pharmacol Res · 1999
Health benefits of docosahexaenoic acid (DHA).
Cell Mol Life Sci · 2005
Surface exposure of phosphatidylserine in pathological cells.
J Neurosci · 2000
Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen.
Circulation · 2010
OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction.
Guides & Resources
Exercise and Brain Health: How Physical Activity Supports Cognitive Function
Physical exercise is one of the most robustly supported interventions for brain health, with evidence spanning epidemiological studies, randomized controlled trials, and mechanistic neuroscience research. …
lifestyleSleep and Cognitive Performance: Why Rest Is Your Brain's Best Nootropic
Sleep is arguably the single most important factor in cognitive performance, yet it remains the most frequently sacrificed in pursuit of productivity. During sleep, the …
safetyCaffeine and L-Theanine: Synergy, Dosing, and Important Cautions
The combination of caffeine and L-theanine is often cited as the most well-studied nootropic stack, and for good reason. Multiple randomized controlled trials have demonstrated …
Evidence Grading System
Every supplement claim on this site is graded on an A–D scale based on peer-reviewed clinical research from PubMed. Our algorithm evaluates study design (RCTs rank highest), consistency of results, sample sizes, and the overall body of evidence. No manufacturer sponsorship influences our grades.
Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.
At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.
Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.
In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.
How It Works
Sin anuncios. Sin clasificaciones patrocinadas. Solo ciencia.
Centro de investigación
Buscamos en PubMed cada estudio clínico sobre ingredientes de suplementos.
Extracción
Extraemos los hallazgos clave — tamaños de muestra, tipos de estudio y resultados.
Grados A a F
Evaluamos la evidencia como un boletín escolar — de A (sólida) a F (negativa).
Respuesta clara
Obtenga una respuesta clara en segundos — ¿este suplemento realmente funciona?
Cited Health Network
Explore evidence-based research across multiple health domains.
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Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.