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Molecular mechanisms of resveratrol action in obesity are mapped, showing SIRT-1 deacetylase activation leading to inhibition of adipogenesis, enhancement of mitochondrial activity and gluconeogenesis via PGC-1alpha, and modulation of inflammatory signaling.
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![Figure 6: Molecular mechanisms of resveratrol action in obesity are mapped, showing SIRT-1 deacetylase activation leading to inhibition of adipogenesis, enhancement of mitochondrial activity and gluconeogenesis via PGC-1alpha, and modulation of inflammatory signaling.]() > Source: Laura M Mongioì et al. "The Role of Resveratrol Administration in Human Obesity.." *International journal of molecular sciences*, 2021. PMID: [33921991](https://pubmed.ncbi.nlm.nih.gov/33921991/)
<figure> <img src="" alt="Molecular mechanisms of resveratrol action in obesity are mapped, showing SIRT-1 deacetylase activation leading to inhibition of adipogenesis, enhancement of mitochondrial activity and gluconeogenesis via PGC-1alpha, and modulation of inflammatory signaling." /> <figcaption>Figure 6. Molecular mechanisms of resveratrol action in obesity are mapped, showing SIRT-1 deacetylase activation leading to inhibition of adipogenesis, enhancement of mitochondrial activity and gluconeogenesis via PGC-1alpha, and modulation of inflammatory signaling.<br> Source: Laura M Mongioì et al. "The Role of Resveratrol Administration in Human Obesity.." <em>International journal of molecular sciences</em>, 2021. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/33921991/">33921991</a></figcaption> </figure>