Resveratrol के लिए Cerebrovascular Health
C साक्ष्य की तुलना करें छोटे अध्ययनों से सीमित साक्ष्य उपलब्ध हैं, लेकिन कुछ सकारात्मक संकेत मौजूद हैं।Research suggests resveratrol may improve cerebral blood flow through nitric oxide-mediated vasodilation and activation of neuroprotective SIRT1 pathways. Bioavailability remains a key challenge.
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C
निष्कर्ष
Research suggests resveratrol may improve cerebral blood flow through nitric oxide-mediated vasodilation and activation of neuroprotective SIRT1 pathways. Bioavailability remains a key challenge.
Key Study Findings
Systematic Review
Investigating the impact of resveratrol and quercetin on glymphatic function, blood-brain barrier, and neuroglial health: …
Dose: None
बनाम: None
Outcome: effects on glymphatic function, BBB permeability, neuroglial health
प्रभाव: None
None
जनसंख्या: experimental models and clinical trials on Alzheimer's, Parkinson's, and multiple sclerosis
Review
Dietary Antioxidants, Polyphenols, and Vascular Health: Insights From Ultrasound Measurement of Carotid Intima-Media Thickness and …
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: older adults and individuals with neurodegenerative disorders
In Vitro
Resveratrol attenuates the CoCl2-induced hypoxia damage by regulation of lysine β-hydroxybutyrylation in PC12 cells.
Dose: None
बनाम: CoCl2-induced hypoxia without resveratrol
Outcome: Cell viability and Kbhb modulation under hypoxia
प्रभाव: None
None
जनसंख्या: PC12 rat pheochromocytoma cells
Review
Varicella Zoster Virus and Stroke: An Intricate Relationship.
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: None
Controlled Clinical Trial
[Verification of resveratrol ameliorating vascular endothelial damage in sepsis-associated encephalopathy through HIF-1α pathway based on …
Dose: 40 or 60 mg/kg
बनाम: CLP group (0.9% NaCl)
Outcome: Cerebrovascular endothelial barrier function
प्रभाव: None
None
जनसंख्या: CLP-induced sepsis-associated encephalopathy mice
Review
The Roles of Flavonoids and Other Plant-Based Phenolics in Mitigating Diabetes-Induced Macrovascular Complications.
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: Review of flavonoids/phenolics in diabetic macrovascular
Key Statistics
8
अध्ययन
600
प्रतिभागी
↑
Positive
C
ग्रेड
Referenced Papers
Investigating the impact of resveratrol and quercetin on glymphatic function, blood-brain barrier, and neuroglial health: A systematic review.
Systematic Review
Brain research
2026
2 उद्धरण
Phytotherapy research : …
2026
BMC neurology
2025
3 उद्धरण
Phytotherapy research : …
2025
1 उद्धरण
Brain research
2025
1 उद्धरण
Viruses
2025
1 उद्धरण
Zhongguo Zhong yao …
2025
Cardiovascular & hematological …
2025
Phytotherapy research : …
2025
Journal of applied …
2025
Frontiers in pharmacology
2024
14 उद्धरण
International journal of …
2024
1 उद्धरण
Aging
2023
3 उद्धरण
IBRO neuroscience reports
2023
1 उद्धरण
The Role of Resveratrol in Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review.
Systematic Review
Journal of medicinal …
2022
48 उद्धरण
Frontiers in pharmacology
2022
37 उद्धरण
Biomedicine & pharmacotherapy …
2022
34 उद्धरण
Cellular and molecular …
2022
20 उद्धरण
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies.
Systematic Review
Phytotherapy research : …
2022
13 उद्धरण
Acta biochimica Polonica
2022
10 उद्धरण
Nutrients
2022
9 उद्धरण
Nutrients
2022
2 उद्धरण
Clinical nutrition (Edinburgh, …
2021
54 उद्धरण
International journal of …
2021
50 उद्धरण
Frontiers in cellular …
2021
40 उद्धरण
Journal of bone …
2020
120 उद्धरण
Nutrients
2020
49 उद्धरण
Experimental and therapeutic …
2019
25 उद्धरण
International journal of …
2019
11 उद्धरण
Cerebral Blood Flow Measurements in Adults: A Review on the Effects of Dietary Factors and Exercise.
Review
Nutrients
2018
108 उद्धरण
Nutrients
2018
77 उद्धरण
The American journal …
2018
29 उद्धरण
Frontiers in aging …
2018
23 उद्धरण
Nutrients
2017
149 उद्धरण
Oxidative medicine and …
2017
87 उद्धरण
Menopause (New York, …
2017
47 उद्धरण
Nutrition, metabolism, and …
2016
85 उद्धरण
Nutrients
2016
83 उद्धरण
Nutrients
2016
38 उद्धरण
Postepy higieny i …
2016
13 उद्धरण
Journal of agricultural …
2014
58 उद्धरण
Integrative medicine research
2014
51 उद्धरण
Food and chemical …
2013
188 उद्धरण
Annals of the …
2013
31 उद्धरण
Journal of cerebral …
2011
61 उद्धरण
American journal of …
2011
60 उद्धरण
Ageing research reviews
2010
228 उद्धरण
The Journal of …
2010
83 उद्धरण
Genes & nutrition
2010
64 उद्धरण
Journal of cardiovascular …
2009
297 उद्धरण
Alcoholism, clinical and …
2009
238 उद्धरण
Frontiers in aging …
2009
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- general:
- 150-500 mg/day trans-resveratrol
- cognitivesupport:
- 200-500 mg/day
अधिकतम सीमा: 5,000 mg/day (highest dose in clinical trials)
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| 40 or 60 mg/kg | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
सेवन का सर्वोत्तम समय: With meals containing fat; morning preferred
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Gastrointestinal discomfort
- ⚠ Headache
- ⚠ Diarrhea at high doses
ज्ञात अंतःक्रियाएँ
- ● Anticoagulants (may increase bleeding risk)
- ● CYP450 substrates (affects drug metabolism)
- ● Estrogen-sensitive conditions (weak estrogenic activity)
सहनीय अधिकतम सेवन: 5,000 mg/day (highest dose in clinical trials)
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Resveratrol help with Cerebrovascular Health?
Based on 8 studies with 600 participants, there is limited but promising evidence that Resveratrol may support Cerebrovascular Health management. Our evidence grade is C (Some Evidence).
How much Resveratrol should I take for Cerebrovascular Health?
Studies have used various dosages. A commonly studied range is 150-500 mg/day trans-resveratrol. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort, Headache, Diarrhea at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and Cerebrovascular Health?
We rate the evidence as Grade C (Some Evidence). This rating is based on 8 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
Related Evidence
इसके लिए अन्य सामग्री Cerebrovascular Health
References
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FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।