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Baseline characterization of vascular function in MTHFR-deficient models, comparing vessel responses between wild-type and MTHFR C677T variant carriers. The data illustrate the extent of vascular dysfunction associated with this genetic polymorphism.

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![Figure 1: Baseline characterization of vascular function in MTHFR-deficient models, comparing vessel responses between wild-type and MTHFR C677T variant carriers. The data illustrate the extent of vascular dysfunction associated with this genetic polymorphism.]()

> Source: Albino Carrizzo et al. "SIRT1 pharmacological activation rescues vascular dysfunction and prevents throm." *Cellular and molecular life sciences : CMLS*, 2022. PMID: [35821533](https://pubmed.ncbi.nlm.nih.gov/35821533/)
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  <img src="" alt="Baseline characterization of vascular function in MTHFR-deficient models, comparing vessel responses between wild-type and MTHFR C677T variant carriers. The data illustrate the extent of vascular dysfunction associated with this genetic polymorphism." />
  <figcaption>Figure 1. Baseline characterization of vascular function in MTHFR-deficient models, comparing vessel responses between wild-type and MTHFR C677T variant carriers. The data illustrate the extent of vascular dysfunction associated with this genetic polymorphism.<br>  Source: Albino Carrizzo et al. "SIRT1 pharmacological activation rescues vascular dysfunction and prevents throm." <em>Cellular and molecular life sciences : CMLS</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35821533/">35821533</a></figcaption>
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