Omega-3 Fatty Acids (DHA/EPA) untuk Cerebrovascular Health
BDHA supports vascular endothelial function and may help reduce neuroinflammation. In CAD patients, 3.36 g/day supplementation was associated with slowed cognitive aging equivalent to approximately 2.5 years.
Kesimpulan
DHA supports vascular endothelial function and may help reduce neuroinflammation. In CAD patients, 3.36 g/day supplementation was associated with slowed cognitive aging equivalent to approximately 2.5 years.
Key Study Findings
Populasi: narrative review of ashwagandha clinical trials and basic research (1994-present)
Populasi: APP/PS1 transgenic Alzheimer's disease mouse model
Populasi: Children with autism spectrum disorder
Populasi: Dementia-free UK Biobank participants aged 40-69
Populasi: Simulated CVD disease population (in silico study)
Key Statistics
12
Studi
2000
Peserta
Positive
Peringkat
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 1,000-2,000 mg combined DHA/EPA per day
- cognitivesupport:
- 1,000-1,700 mg/day (optimal dose-response curve)
Batas atas: 3,000 mg/day combined DHA/EPA (FDA GRAS)
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | 10 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 215624 |
| 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL | -- | Positive | -- |
| EPA 180mg + DHA 120mg | 26 weeks | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
Waktu terbaik diminum: With meals containing fat for better absorption
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Fishy aftertaste or burping
- ⚠ Mild gastrointestinal discomfort
- ⚠ Potential increased bleeding time at very high doses
- ⚠ May lower blood pressure slightly
Interaksi yang Diketahui
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
- ● Blood pressure medications (additive hypotensive effect)
- ● Orlistat (may reduce omega-3 absorption)
Asupan atas yang dapat ditoleransi: 3,000 mg/day combined DHA/EPA (FDA GRAS)
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Omega-3 Fatty Acids (DHA/EPA) help with Cerebrovascular Health?
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Are there side effects of Omega-3 Fatty Acids (DHA/EPA)?
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Related Evidence
Bahan lain untuk Cerebrovascular Health
Omega-3 Fatty Acids (DHA/EPA) untuk kondisi lain
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