Resveratrol 관련 Cerebrovascular Health
CResearch suggests resveratrol may improve cerebral blood flow through nitric oxide-mediated vasodilation and activation of neuroprotective SIRT1 pathways. Bioavailability remains a key challenge.
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C
결론
Research suggests resveratrol may improve cerebral blood flow through nitric oxide-mediated vasodilation and activation of neuroprotective SIRT1 pathways. Bioavailability remains a key challenge.
Key Study Findings
Systematic Review
Investigating the impact of resveratrol and quercetin on glymphatic function, blood-brain barrier, and neuroglial health: …
Dose: None
vs: None
Outcome: effects on glymphatic function, BBB permeability, neuroglial health
효과: None
None
대상 집단: experimental models and clinical trials on Alzheimer's, Parkinson's, and multiple sclerosis
Review
Dietary Antioxidants, Polyphenols, and Vascular Health: Insights From Ultrasound Measurement of Carotid Intima-Media Thickness and …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: older adults and individuals with neurodegenerative disorders
In Vitro
Resveratrol attenuates the CoCl2-induced hypoxia damage by regulation of lysine β-hydroxybutyrylation in PC12 cells.
Dose: None
vs: CoCl2-induced hypoxia without resveratrol
Outcome: Cell viability and Kbhb modulation under hypoxia
효과: None
None
대상 집단: PC12 rat pheochromocytoma cells
Review
Natural Products and Exercise Synergy: Unraveling Molecular Mechanisms to Enhance Brain Function in Alzheimer's Disease.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Controlled Clinical Trial
[Verification of resveratrol ameliorating vascular endothelial damage in sepsis-associated encephalopathy through HIF-1α pathway based on …
Dose: 40 or 60 mg/kg
vs: CLP group (0.9% NaCl)
Outcome: Cerebrovascular endothelial barrier function
효과: None
None
대상 집단: CLP-induced sepsis-associated encephalopathy mice
Systematic Review
The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.
Dose: None
vs: Placebo or no treatment
Outcome: Cardiometabolic changes in menopausal women
효과: None
None
대상 집단: Menopausal women
Key Statistics
8
연구
600
참여자
↑
Positive
C
등급
Referenced Papers
Investigating the impact of resveratrol and quercetin on glymphatic function, blood-brain barrier, and neuroglial health: A systematic review.
Systematic Review
Brain research
2026
2 인용
Phytotherapy research : …
2026
BMC neurology
2025
3 인용
Phytotherapy research : …
2025
1 인용
Brain research
2025
1 인용
Viruses
2025
1 인용
Zhongguo Zhong yao …
2025
Cardiovascular & hematological …
2025
Phytotherapy research : …
2025
Journal of applied …
2025
Frontiers in pharmacology
2024
14 인용
International journal of …
2024
1 인용
Aging
2023
3 인용
IBRO neuroscience reports
2023
1 인용
The Role of Resveratrol in Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review.
Systematic Review
Journal of medicinal …
2022
48 인용
Frontiers in pharmacology
2022
37 인용
Biomedicine & pharmacotherapy …
2022
34 인용
Cellular and molecular …
2022
20 인용
Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies.
Systematic Review
Phytotherapy research : …
2022
13 인용
Acta biochimica Polonica
2022
10 인용
Nutrients
2022
9 인용
Nutrients
2022
2 인용
Clinical nutrition (Edinburgh, …
2021
54 인용
International journal of …
2021
50 인용
Frontiers in cellular …
2021
40 인용
Journal of bone …
2020
120 인용
Nutrients
2020
49 인용
Experimental and therapeutic …
2019
25 인용
International journal of …
2019
11 인용
Cerebral Blood Flow Measurements in Adults: A Review on the Effects of Dietary Factors and Exercise.
Review
Nutrients
2018
108 인용
Nutrients
2018
77 인용
The American journal …
2018
29 인용
Frontiers in aging …
2018
23 인용
Nutrients
2017
149 인용
Oxidative medicine and …
2017
87 인용
Menopause (New York, …
2017
47 인용
Nutrition, metabolism, and …
2016
85 인용
Nutrients
2016
83 인용
Nutrients
2016
38 인용
Postepy higieny i …
2016
13 인용
Journal of agricultural …
2014
58 인용
Integrative medicine research
2014
51 인용
Food and chemical …
2013
188 인용
Annals of the …
2013
31 인용
Journal of cerebral …
2011
61 인용
American journal of …
2011
60 인용
Ageing research reviews
2010
228 인용
The Journal of …
2010
83 인용
Genes & nutrition
2010
64 인용
Journal of cardiovascular …
2009
297 인용
Alcoholism, clinical and …
2009
238 인용
Frontiers in aging …
2009
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 150-500 mg/day trans-resveratrol
- cognitivesupport:
- 200-500 mg/day
상한량: 5,000 mg/day (highest dose in clinical trials)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| 40 or 60 mg/kg | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| 250 mg single dose | -- | Positive | 16 |
권장 복용 시간: With meals containing fat; morning preferred
Safety & Side Effects
보고된 부작용
- ⚠ Gastrointestinal discomfort
- ⚠ Headache
- ⚠ Diarrhea at high doses
알려진 상호작용
- ● Anticoagulants (may increase bleeding risk)
- ● CYP450 substrates (affects drug metabolism)
- ● Estrogen-sensitive conditions (weak estrogenic activity)
일일 최대 섭취 허용량: 5,000 mg/day (highest dose in clinical trials)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Resveratrol help with Cerebrovascular Health?
Based on 8 studies with 600 participants, there is limited but promising evidence that Resveratrol may support Cerebrovascular Health management. Our evidence grade is C (Some Evidence).
How much Resveratrol should I take for Cerebrovascular Health?
Studies have used various dosages. A commonly studied range is 150-500 mg/day trans-resveratrol. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort, Headache, Diarrhea at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and Cerebrovascular Health?
We rate the evidence as Grade C (Some Evidence). This rating is based on 8 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: Cerebrovascular Health
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.