Vitamin D 관련 Nutritional Deficiency Cognitive Impairment

Q: Does Vitamin D help with Nutritional Deficiency Cognitive Impairment?

Based on 20 studies with 4,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Nutritional Deficiency Cognitive Impairment management. Our evidence grade is B (Good Evidence).

Q: How much Vitamin D should I take for Nutritional Deficiency Cognitive Impairment?

Studies have used various dosages. A commonly studied range is 600-2,000 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Vitamin D?

Reported side effects may include Hypercalcemia at very high doses, Nausea and vomiting, Kidney stones (rare, high doses), Weakness and fatigue. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Vitamin D and Nutritional Deficiency Cognitive Impairment?

We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 4,500 total participants. The overall direction of effect is positive.

Vitamin D deficiency is identified as a critical risk factor for cognitive decline. 40% of geriatric memory clinic patients are D-deficient. Co-supplementation with B12 and folate appears to provide synergistic cognitive support.

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결론

Key Study Findings

Observational Study n=2582

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the …

Dose: None vs: None Outcome: Cognitive impairment risk 효과: OR=0.695 (Vit D); OR=0.777 (FA) p=0.003 (Vit D); p=0.034 (FA)

대상 집단: Elderly participants aged 60+ from NHANES 2011-2014

Review

B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges.

Dose: None vs: None Outcome: Pregnancy outcomes and offspring neurodevelopment 효과: None None

대상 집단: Pregnant women (review)

Meta-Analysis

Effects of vitamins and polyunsaturated fatty acids on cognitive function in older adults with mild …

Dose: None vs: Control Outcome: Cognitive function 효과: SMD = 0.58, 95% CI = [0.20, 0.96] P = 0.003

대상 집단: Patients with mild cognitive impairment

Other

Dietary Clostridium butyricum and 25-Hydroxyvitamin D3 modulate bone metabolism of broilers through the gut-brain axis.

Dose: 75 mg vs: None Outcome: Body weight 효과: None P < 0.05

대상 집단: Rat model

Controlled Clinical Trial

Targeting neuroendocrine abnormalities in Parkinson's disease with exercise.

Dose: None vs: None Outcome: neuroprotection 효과: None None

대상 집단: None

RCT n=65 36 weeks Double-blind

Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: …

Dose: 4 capsules daily, each containing: beta-glucan 250 mg + vitamin D3 3.75 µg + vitamin B6 1.05 mg + zi vs: Placebo 효과: significant improvement in cognitive fatigue (FIS-40); p = 0.0338 0.0338

Key Statistics

연구

4500

참여자

↑

Positive

등급

Referenced Papers

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. Other

Brain and behavior 2026

B-vitamins and one-carbon metabolism during pregnancy: health impacts and challenges. Review

The Proceedings of … 2025 5 인용

Effects of vitamins and polyunsaturated fatty acids on cognitive function in older adults with mild cognitive impairment: a meta-analysis of … Meta-Analysis

European journal of … 2024 16 인용

Dietary Clostridium butyricum and 25-Hydroxyvitamin D3 modulate bone metabolism of broilers through the gut-brain axis. Other

Poultry science 2024 9 인용

Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. RCT

Nutrients 2023 9 인용

Targeting neuroendocrine abnormalities in Parkinson's disease with exercise. Other

Frontiers in neuroscience 2023 5 인용

Serum brain-derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case-control … Other

Journal of cosmetic … 2023 3 인용

The relationship between neuropsychological function and responsiveness to vitamin D supplementation using artificial neural networks. Other

Nutrition and health 2020 4 인용

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life. Meta-Analysis

The Cochrane database … 2018 123 인용

Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review. Review

The journal of … 2017 75 인용

Effect of Vitamin Intake on Cognitive Decline in Older Adults: Evaluation of the Evidence. Review

The journal of … 2015 25 인용

[Vitamins and nutritional supplements in older persons: How to diagnose and when to substitute?]. Review

Der Internist 2015 3 인용

Influence of mineral and vitamin supplements on pregnancy outcome. Review

European journal of … 2012 225 인용

Multivitamin/mineral supplements and prevention of chronic disease. Review

Evidence report/technology assessment 2006

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:: 600-2,000 IU/day
deficiencycorrection:: 4,000-5,000 IU/day

상한량: 4,000 IU/day (IOM); 10,000 IU/day (Endocrine Society upper safety)

연구에서 사용된 용량

용량	기간	효과	N
None	--	Positive	2582
None	--	Positive	--
None	--	Positive	--
75 mg	--	Neutral	--
None	--	Positive	--
4 capsules daily, each containing: beta-glucan 250 mg + vitamin D3 3.75 µg + vitamin B6 1.05 mg + zi	36 weeks	Positive	65
None	--	Negative	90
50000 IU/week	9 weeks	Positive	619

권장 복용 시간: With meals containing fat; morning preferred

Safety & Side Effects

보고된 부작용

⚠ Hypercalcemia at very high doses
⚠ Nausea and vomiting
⚠ Kidney stones (rare, high doses)
⚠ Weakness and fatigue

알려진 상호작용

● Corticosteroids (reduce calcium absorption)
● Statins (both affect cholesterol pathways)
● Thiazide diuretics (additive calcium retention)
● Weight loss drugs (may reduce vitamin D absorption)

일일 최대 섭취 허용량: 4,000 IU/day (IOM); 10,000 IU/day (Endocrine Society upper safety)

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does Vitamin D help with Nutritional Deficiency Cognitive Impairment?

Based on 20 studies with 4,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Nutritional Deficiency Cognitive Impairment management. Our evidence grade is B (Good Evidence).

How much Vitamin D should I take for Nutritional Deficiency Cognitive Impairment?

Studies have used various dosages. A commonly studied range is 600-2,000 IU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin D?

Reported side effects may include Hypercalcemia at very high doses, Nausea and vomiting, Kidney stones (rare, high doses), Weakness and fatigue. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin D and Nutritional Deficiency Cognitive Impairment?

We rate the evidence as Grade B (Good Evidence). This rating is based on 20 peer-reviewed studies with 4,500 total participants. The overall direction of effect is positive.

Related Evidence

Vitamin D 다른 건강 상태에 대한 근거

Depression-Related Cognitive Dysfunction C

한눈에 보기

Evidence Strength72%

High confidence

연구 분석

RCT (1)Meta (2)Other (17)

대안 비교

이 건강 상태에 대한 다른 성분의 비교 결과를 확인하세요.

모든 성분 보기: Nutritional Deficiency Cognitive Impairment

자세히 알아보기

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.