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Ceramide biosynthesis pathways and their contribution to neurodegeneration are depicted. Elevated ceramide levels are associated with increased oxidative stress and apoptosis in brain tissue.

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![Figure 3: Ceramide biosynthesis pathways and their contribution to neurodegeneration are depicted. Elevated ceramide levels are associated with increased oxidative stress and apoptosis in brain tissue.]()

> Source: Domenico Sergi et al. "Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The I." *International journal of molecular sciences*, 2023. PMID: [36901834](https://pubmed.ncbi.nlm.nih.gov/36901834/)
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  <img src="" alt="Ceramide biosynthesis pathways and their contribution to neurodegeneration are depicted. Elevated ceramide levels are associated with increased oxidative stress and apoptosis in brain tissue." />
  <figcaption>Figure 3. Ceramide biosynthesis pathways and their contribution to neurodegeneration are depicted. Elevated ceramide levels are associated with increased oxidative stress and apoptosis in brain tissue.<br>  Source: Domenico Sergi et al. "Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The I." <em>International journal of molecular sciences</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36901834/">36901834</a></figcaption>
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