Vitamin E untuk Age-Related Cognitive Decline
C Bukti Bukti terbatas dari studi kecil, namun beberapa sinyal positif ada.High-dose vitamin E may slow functional decline in moderate Alzheimer's disease (TEAM-AD trial). Results are mixed for cognitive decline prevention in healthy populations.
Kesimpulan
High-dose vitamin E may slow functional decline in moderate Alzheimer's disease (TEAM-AD trial). Results are mixed for cognitive decline prevention in healthy populations.
Key Study Findings
Populasi: participants from 43 clinical studies (2012-2022)
Populasi: None
Populasi: Alzheimer's disease patients
Populasi: NHANES adults aged ≥60 years (2011-2014)
Populasi: Review of vitamins in neurodegeneration
Populasi: Elderly with or at risk of Alzheimer's disease (review)
Key Statistics
12
Studi
3000
Peserta
Mixed
Peringkat
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 15 mg/day (RDA)
- cognitivesupport:
- 400-800 IU/day
Batas atas: 1,000 mg/day (1,500 IU natural / 1,100 IU synthetic)
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Positive | 80488 |
| None | -- | Mixed | -- |
| Curcumin 800mg/d, omega-3 2g/d, resveratrol 600mg/d | -- | Mixed | -- |
| Inflection at 29.65 g/day (DSST), 22.65 g/day (composite) | -- | Positive | 2713 |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| >=112 mg/day vs <112 mg/day | 270 weeks | Positive | 1550 |
Waktu terbaik diminum: With meals containing fat
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Increased bleeding risk at high doses
- ⚠ Nausea and diarrhea
- ⚠ Fatigue and weakness
- ⚠ Blurred vision
Interaksi yang Diketahui
- ● Anticoagulants (increased bleeding risk)
- ● Statins and niacin (may reduce HDL-raising effects)
- ● Chemotherapy and radiation (may reduce efficacy)
Asupan atas yang dapat ditoleransi: 1,000 mg/day (1,500 IU natural / 1,100 IU synthetic)
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Vitamin E help with Age-Related Cognitive Decline?
How much Vitamin E should I take for Age-Related Cognitive Decline?
Are there side effects of Vitamin E?
How strong is the evidence for Vitamin E and Age-Related Cognitive Decline?
Related Evidence
Bahan lain untuk Age-Related Cognitive Decline
References
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