Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot Study.

Isabel Barros Hübner, Denise Bisolo Scheibe, Josemar Marchezan, Joana Bücker

RCT Clinical neuropharmacology None 2 citations

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Study Design

Study Type: Randomized Controlled Trial
Population: pediatric patients aged 7-12 years diagnosed with ADHD

Intervention: Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot Study. None
Comparator: placebo
Primary Outcome: ADHD symptom improvement
Effect Direction: Neutral
Risk of Bias: Moderate

Abstract

OBJECTIVES: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurobehavioral disorder in school-aged children. Although there are several drug treatment options, some patients do not have adequate therapeutic responses to conventional medications or experience considerable adverse effects. Citicoline is an endogenous molecule that has beneficial effects on attention, impulsivity, and memory and is a potential treatment for ADHD. This study aimed to evaluate the effect of citicoline in pediatric patients diagnosed with ADHD. METHODS: This randomized, crossover, double-blind, placebo-controlled clinical trial included with patients aged 7-12 years diagnosed with ADHD. RESULTS: As a result, no statistically significant difference was noted between the use of citicoline and placebo in the evaluated parameters. The treatment had no adverse effects. CONCLUSIONS: Citicoline seems to be a safe molecule to be administered in the pediatric age group. Further studies are required to assess the therapeutic potential of citicoline in ADHD.

TL;DR

Citicoline seems to be a safe molecule to be administered in the pediatric age group and has no adverse effects, and further studies are required to assess the therapeutic potential of citicoline in ADHD.

Used In Evidence Reviews

B Citicoline for Attention & Focus Difficulties

Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot Study.

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Study Design

Abstract

TL;DR

Used In Evidence Reviews

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