Rhodiola rosea pour Mental Fatigue

Q: Does Rhodiola rosea help with Mental Fatigue?

Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).

Q: How much Rhodiola rosea should I take for Mental Fatigue?

Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Rhodiola rosea?

Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Rhodiola rosea and Mental Fatigue?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Multiple RCTs demonstrate significant reduction in mental fatigue and improved concentration during stressful periods. Rosavin and salidroside appear to be the primary active compounds supporting cognitive endurance.

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En conclusion

Key Study Findings

Randomized Controlled Trial n=18 Double-blind

The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises …

Dose: 4 days supplementation vs: Placebo Outcome: Strength performance in bench-press and bench-pull Effet: 17 small ESs observed, 14 favoring RR None

Population: Young healthy individuals (7 women, 11 men)

Review

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on …

Dose: None vs: None Outcome: Inflammatory markers Effet: None None

Population: Depression patients

Randomized Controlled Trial 4.3 weeks Single-blind

Assessing brain function in stressed healthy individuals following the use of a combination of green …

Dose: None vs: placebo Outcome: Brain response to stress and quality of life Effet: None p = 0.001

Population: Chronically stressed but healthy subjects

Review

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.

Dose: None vs: None Outcome: None Effet: None None

Population: None

Other 4 weeks

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance …

Dose: None vs: Control group Outcome: acute and chronic effects of resistance exercise coupled … Effet: None p < 0.05

Population: None

Review

Adaptogens in mental and behavioral disorders.

Dose: None vs: None Outcome: Stress-protective and stimulative effects Effet: None None

Population: Adults with mental and behavioral disorders

Key Statistics

Études

900

Participants

↑

Positive

Note

Referenced Papers

The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue … RCT

Nutrients 2025 6 citations

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea. Review

Journal of neural … 2024 8 citations

Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B … Other

Frontiers in nutrition 2023 3 citations

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review. Review

Journal of clinical … 2021 38 citations

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis … Other

Journal of the … 2020 25 citations

Adaptogens in mental and behavioral disorders. Review

The Psychiatric clinics … 2013 64 citations

Rhodiola rosea for physical and mental fatigue: a systematic review. Systematic Review

BMC complementary and … 2012 114 citations

Does Rhodiola rosea possess ergogenic properties? Review

International journal of … 2006 40 citations

[Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine]. Review

Medicina (Kaunas, Lithuania) 2004

A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for … RCT

Phytomedicine : international … 2003 205 citations

Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen … RCT

Phytomedicine : international … 2000 281 citations

A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of … RCT

Phytomedicine : international … 2000 251 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:: 200-600 mg/day standardized to 3% rosavins and 1% salidroside

Limite supérieure : Not established; doses up to 680 mg/day used in trials

Posologies étudiées dans la recherche

Posologie	Durée	Effet	N
4 days supplementation	--	Positive	18
None	--	Mixed	--
None	4.3 weeks	Positive	--
None	--	Mixed	--
None	4 weeks	Mixed	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	--

Moment optimal de prise : Morning on empty stomach; avoid evening (may be stimulating)

Safety & Side Effects

Effets indésirables signalés

⚠ Insomnia or overstimulation (if taken late)
⚠ Dry mouth
⚠ Dizziness
⚠ Mild agitation

Interactions connues

● Antidepressants (SSRIs, MAOIs — additive serotonergic effects)
● Antidiabetic drugs (may lower blood sugar)
● Stimulant medications (additive stimulatory effects)
● Immunosuppressants (may modulate immune response)

Apport maximal tolérable : Not established; doses up to 680 mg/day used in trials

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Rhodiola rosea help with Mental Fatigue?

Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).

How much Rhodiola rosea should I take for Mental Fatigue?

Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Rhodiola rosea?

Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Rhodiola rosea and Mental Fatigue?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Related Evidence

Autres ingrédients pour Mental Fatigue

Creatine B Panax Ginseng C

Rhodiola rosea pour d'autres pathologies

Stress-Induced Cognitive Decline B

Verdict rapide

Evidence Strength72%

High confidence

Synthèse des études

RCT (4)Meta (0)Other (7)

Comparer les alternatives

Découvrez comment d'autres ingrédients se comparent pour cette condition.Découvrez comment d'autres ingrédients se comparent pour cette pathologie.

Voir tous les ingrédients pour Mental Fatigue

En savoir plus

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.