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Rhodiola rosea untuk Mental Fatigue

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Multiple RCTs demonstrate significant reduction in mental fatigue and improved concentration during stressful periods. Rosavin and salidroside appear to be the primary active compounds supporting cognitive endurance.

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Kesimpulan

Multiple RCTs demonstrate significant reduction in mental fatigue and improved concentration during stressful periods. Rosavin and salidroside appear to be the primary active compounds supporting cognitive endurance.

Key Study Findings

Randomized Controlled Trial n=18 Double-blind
The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises …
Dose: 4 days supplementation vs: Placebo Outcome: Strength performance in bench-press and bench-pull Efek: 17 small ESs observed, 14 favoring RR None

Populasi: Young healthy individuals (7 women, 11 men)

Review
Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on …
Dose: None vs: None Outcome: Inflammatory markers Efek: None None

Populasi: Depression patients

Randomized Controlled Trial 4.3 weeks Single-blind
Assessing brain function in stressed healthy individuals following the use of a combination of green …
Dose: None vs: placebo Outcome: Brain response to stress and quality of life Efek: None p = 0.001

Populasi: Chronically stressed but healthy subjects

Review
The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.
Dose: None vs: None Outcome: None Efek: None None

Populasi: None

Other 4 weeks
Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance …
Dose: None vs: Control group Outcome: acute and chronic effects of resistance exercise coupled … Efek: None p < 0.05

Populasi: None

Review
Adaptogens in mental and behavioral disorders.
Dose: None vs: None Outcome: Stress-protective and stimulative effects Efek: None None

Populasi: Adults with mental and behavioral disorders

Key Statistics

11

Studi

900

Peserta

Positive

B

Peringkat

Referenced Papers

The Psychiatric clinics … 2013 64 sitasi
BMC complementary and … 2012 114 sitasi
International journal of … 2006 40 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
200-600 mg/day standardized to 3% rosavins and 1% salidroside

Batas atas: Not established; doses up to 680 mg/day used in trials

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
4 days supplementation -- Positive 18
None -- Mixed --
None 4.3 weeks Positive --
None -- Mixed --
None 4 weeks Mixed --
None -- Positive --
None -- Positive --
None -- Mixed --

Waktu terbaik diminum: Morning on empty stomach; avoid evening (may be stimulating)

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Insomnia or overstimulation (if taken late)
  • Dry mouth
  • Dizziness
  • Mild agitation

Interaksi yang Diketahui

  • Antidepressants (SSRIs, MAOIs — additive serotonergic effects)
  • Antidiabetic drugs (may lower blood sugar)
  • Stimulant medications (additive stimulatory effects)
  • Immunosuppressants (may modulate immune response)

Asupan atas yang dapat ditoleransi: Not established; doses up to 680 mg/day used in trials

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Rhodiola rosea help with Mental Fatigue?
Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).
How much Rhodiola rosea should I take for Mental Fatigue?
Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Rhodiola rosea?
Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Rhodiola rosea and Mental Fatigue?
We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Bahan lain untuk Mental Fatigue

Rhodiola rosea untuk kondisi lain

References

  1. [1] Daniel Marcos-Frutos et al.. Nutrients. 2025. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue … doi:10.3390/nu17060940 PubMed
  2. [2] Juliane K Mueller et al.. J Neural Transm (Vienna). 2024. Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea. doi:10.1007/s00702-024-02749-3 PubMed
  3. [3] Gisèle Pickering et al.. Front Nutr. 2023. Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B … doi:10.3389/fnut.2023.1211321 PubMed
  4. [4] John E Lewis et al.. J Clin Transl Res. 2021. The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review. PubMed
  5. [5] Rémi Roumanille et al.. J Int Soc Sports Nutr. 2020. Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis … doi:10.1186/s12970-020-00390-5 PubMed
  6. [6] Alexander G Panossian. Psychiatr Clin North Am. 2013. Adaptogens in mental and behavioral disorders. doi:10.1016/j.psc.2012.12.005 PubMed
  7. [7] Sana Ishaque et al.. BMC Complement Altern Med. 2012. Rhodiola rosea for physical and mental fatigue: a systematic review. doi:10.1186/1472-6882-12-70 PubMed
  8. [8] Thomas B Walker et al.. Int J Sport Nutr Exerc Metab. 2006. Does Rhodiola rosea possess ergogenic properties? doi:10.1123/ijsnem.16.3.305 PubMed
  9. [9] Agne Kucinskaite et al.. Medicina (Kaunas). 2004. [Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine]. PubMed
  10. [10] V A Shevtsov et al.. Phytomedicine. 2003. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for … doi:10.1078/094471103321659780 PubMed
  11. [11] V Darbinyan et al.. Phytomedicine. 2000. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen … doi:10.1016/S0944-7113(00)80055-0 PubMed
  12. [12] A A Spasov et al.. Phytomedicine. 2000. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of … doi:10.1016/S0944-7113(00)80078-1 PubMed

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