Rhodiola rosea para Mental Fatigue

Q: Does Rhodiola rosea help with Mental Fatigue?

Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).

Q: How much Rhodiola rosea should I take for Mental Fatigue?

Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Rhodiola rosea?

Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Rhodiola rosea and Mental Fatigue?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Multiple RCTs demonstrate significant reduction in mental fatigue and improved concentration during stressful periods. Rosavin and salidroside appear to be the primary active compounds supporting cognitive endurance.

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Conclusão

Key Study Findings

Randomized Controlled Trial n=18 Double-blind

The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises …

Dose: 4 days supplementation vs: Placebo Outcome: Strength performance in bench-press and bench-pull Efeito: 17 small ESs observed, 14 favoring RR None

População: Young healthy individuals (7 women, 11 men)

Review

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on …

Dose: None vs: None Outcome: Inflammatory markers Efeito: None None

População: Depression patients

Randomized Controlled Trial 4.3 weeks Single-blind

Assessing brain function in stressed healthy individuals following the use of a combination of green …

Dose: None vs: placebo Outcome: Brain response to stress and quality of life Efeito: None p = 0.001

População: Chronically stressed but healthy subjects

Review

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.

Dose: None vs: None Outcome: None Efeito: None None

População: None

Other 4 weeks

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance …

Dose: None vs: Control group Outcome: acute and chronic effects of resistance exercise coupled … Efeito: None p < 0.05

População: None

Review

Adaptogens in mental and behavioral disorders.

Dose: None vs: None Outcome: Stress-protective and stimulative effects Efeito: None None

População: Adults with mental and behavioral disorders

Key Statistics

Estudos

900

Participantes

↑

Positive

Nota

Referenced Papers

The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue … RCT

Nutrients 2025 6 citações

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea. Review

Journal of neural … 2024 8 citações

Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B … Other

Frontiers in nutrition 2023 3 citações

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review. Review

Journal of clinical … 2021 38 citações

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis … Other

Journal of the … 2020 25 citações

Adaptogens in mental and behavioral disorders. Review

The Psychiatric clinics … 2013 64 citações

Rhodiola rosea for physical and mental fatigue: a systematic review. Systematic Review

BMC complementary and … 2012 114 citações

Does Rhodiola rosea possess ergogenic properties? Review

International journal of … 2006 40 citações

[Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine]. Review

Medicina (Kaunas, Lithuania) 2004

A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for … RCT

Phytomedicine : international … 2003 205 citações

Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen … RCT

Phytomedicine : international … 2000 281 citações

A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of … RCT

Phytomedicine : international … 2000 251 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:: 200-600 mg/day standardized to 3% rosavins and 1% salidroside

Limite superior: Not established; doses up to 680 mg/day used in trials

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
4 days supplementation	--	Positive	18
None	--	Mixed	--
None	4.3 weeks	Positive	--
None	--	Mixed	--
None	4 weeks	Mixed	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	--

Melhor horário: Morning on empty stomach; avoid evening (may be stimulating)

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Insomnia or overstimulation (if taken late)
⚠ Dry mouth
⚠ Dizziness
⚠ Mild agitation

Interações Conhecidas

● Antidepressants (SSRIs, MAOIs — additive serotonergic effects)
● Antidiabetic drugs (may lower blood sugar)
● Stimulant medications (additive stimulatory effects)
● Immunosuppressants (may modulate immune response)

Ingestão máxima tolerável: Not established; doses up to 680 mg/day used in trials

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Rhodiola rosea help with Mental Fatigue?

Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).

How much Rhodiola rosea should I take for Mental Fatigue?

Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Rhodiola rosea?

Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Rhodiola rosea and Mental Fatigue?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Related Evidence

Outros ingredientes para Mental Fatigue

Creatine B Panax Ginseng C

Rhodiola rosea para outras condições

Stress-Induced Cognitive Decline B

Veredito Rápido

Evidence Strength72%

High confidence

Detalhamento dos Estudos

RCT (4)Meta (0)Other (7)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Mental Fatigue

Saiba Mais

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.