Ashwagandha के लिए Sleep-Related Cognitive Impairment

Q: Does Ashwagandha help with Sleep-Related Cognitive Impairment?

Based on 6 studies with 500 participants, there is limited but promising evidence that Ashwagandha may support Sleep-Related Cognitive Impairment management. Our evidence grade is C (Some Evidence).

Q: How much Ashwagandha should I take for Sleep-Related Cognitive Impairment?

Studies have used various dosages. A commonly studied range is 300-600 mg/day of root extract (KSM-66 or Sensoril). Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Ashwagandha?

Reported side effects may include Drowsiness, Gastrointestinal discomfort, Rare: liver injury (with contaminated or high-dose products), Thyroid hormone elevation (may affect thyroid medications). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Ashwagandha and Sleep-Related Cognitive Impairment?

We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Research suggests KSM-66 ashwagandha may help improve sleep quality and next-morning cognitive performance in stressed adults through cortisol modulation.

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निष्कर्ष

Research suggests KSM-66 ashwagandha may help improve sleep quality and next-morning cognitive performance in stressed adults through cortisol modulation.

Key Study Findings

Review

The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A …

Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: narrative review of ashwagandha clinical trials and basic research (1994-present)

preclinical animal/in vitro study

Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice …

Dose: 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL बनाम: Placebo प्रभाव: None None

animal_study

Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in …

Dose: 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) बनाम: Placebo प्रभाव: At 50 mg/kg: 34% decrease in sleep onset time (p<0.0001); 47% increase in sleep duration (p<0.0001); <0.0001

In Vitro

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of …

Dose: ASH root extract 200 mg/kg and 400 mg/kg for 29 days (rat model) बनाम: Placebo प्रभाव: ASH improved locomotor and cognitive deficits, serum hepatotoxicity indices, oxidative stress marker

Key Statistics

अध्ययन

500

प्रतिभागी

↑

Positive

ग्रेड

Referenced Papers

The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A Review. Review

Nutrients 2026

Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice by enhancing the brain-derived neurotrophic … Other

Journal of ethnopharmacology 2025 9 उद्धरण

Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in In Vitro - In Vivo … Other

Preventive nutrition and … 2022 18 उद्धरण

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction of … Other

Journal of ethnopharmacology 2021 69 उद्धरण

Neurodegenerative diseases and Withania somnifera (L.): An update. Review

Journal of ethnopharmacology 2020 85 उद्धरण

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

general:: 300-600 mg/day of root extract (KSM-66 or Sensoril)
cognitivesupport:: 600 mg/day

अधिकतम सीमा: Not established; well-tolerated up to 1,250 mg/day

अनुसंधान में अध्ययन की गई खुराकें

खुराक	अवधि	प्रभाव	N
None	--	Positive	--
60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL	--	Positive	--
10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden)	--	Positive	--
ASH root extract 200 mg/kg and 400 mg/kg for 29 days (rat model)	--	Positive	--

सेवन का सर्वोत्तम समय: With meals; morning or evening depending on individual response

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

⚠ Drowsiness
⚠ Gastrointestinal discomfort
⚠ Rare: liver injury (with contaminated or high-dose products)
⚠ Thyroid hormone elevation (may affect thyroid medications)

ज्ञात अंतःक्रियाएँ

● Thyroid medications (may increase thyroid hormone levels)
● Sedative medications (additive CNS depression)
● Immunosuppressants (may stimulate immune activity)
● Diabetes medications (may lower blood sugar)

सहनीय अधिकतम सेवन: Not established; well-tolerated up to 1,250 mg/day

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Ashwagandha help with Sleep-Related Cognitive Impairment?

Based on 6 studies with 500 participants, there is limited but promising evidence that Ashwagandha may support Sleep-Related Cognitive Impairment management. Our evidence grade is C (Some Evidence).

How much Ashwagandha should I take for Sleep-Related Cognitive Impairment?

Studies have used various dosages. A commonly studied range is 300-600 mg/day of root extract (KSM-66 or Sensoril). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Ashwagandha?

Reported side effects may include Drowsiness, Gastrointestinal discomfort, Rare: liver injury (with contaminated or high-dose products), Thyroid hormone elevation (may affect thyroid medications). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Ashwagandha and Sleep-Related Cognitive Impairment?

We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Related Evidence

इसके लिए अन्य सामग्री Sleep-Related Cognitive Impairment

Melatonin C L-Theanine C Magnesium L-Threonate C Creatine C

Ashwagandha अन्य स्वास्थ्य स्थितियों के लिए

Stress-Induced Cognitive Decline B Anxiety-Related Cognitive Impairment B

संक्षिप्त निष्कर्ष

Research suggests KSM-66 ashwagandha may help improve sleep quality and next-morning cognitive performance in stressed adults through cortisol modulation.

Evidence Strength52%

Moderate confidence

अध्ययन विश्लेषण

RCT (0)Meta (0)Other (6)

विकल्पों की तुलना करें

देखें कि इस स्वास्थ्य स्थिति के लिए अन्य सामग्री की तुलना कैसे है।

इसके लिए सभी सामग्री देखें Sleep-Related Cognitive Impairment

अधिक जानें

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।