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L-Theanine untuk Sleep-Related Cognitive Impairment

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Research suggests L-theanine supports sleep quality without sedation and may improve next-day cognitive performance through enhanced sleep architecture.

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Kesimpulan

Research suggests L-theanine supports sleep quality without sedation and may improve next-day cognitive performance through enhanced sleep architecture.

Key Study Findings

Randomized Controlled Trial 4.3 weeks Single-blind
Assessing brain function in stressed healthy individuals following the use of a combination of green …
Dose: None vs: placebo Outcome: Brain response to stress and quality of life Efek: None p = 0.001

Populasi: Chronically stressed but healthy subjects

Randomized Controlled Trial n=46 10 weeks Double-blind
L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
Dose: 450-900 mg L-theanine daily vs: Placebo Efek: None p=0.73 (anxiety), p=0.35 (inso
Controlled Clinical Trial n=20 8 weeks Open-label
Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
Dose: 250 mg/day vs: Placebo Outcome: HAMD-21 depression score, cognitive function Efek: None pp0.007

Populasi: Patients with major depressive disorder

Key Statistics

6

Studi

400

Peserta

Positive

C

Peringkat

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
100-200 mg/day
withcaffeine:
200 mg L-theanine + 100 mg caffeine

Batas atas: 900 mg/day (no adverse effects observed in studies)

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
None 4.3 weeks Positive --
450-900 mg L-theanine daily 10 weeks Neutral 46
250 mg/day 8 weeks Positive 20

Waktu terbaik diminum: Morning or as needed; rapid onset (30-60 minutes)

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Generally very well-tolerated
  • Mild drowsiness in sensitive individuals
  • Mild headache (rare)

Interaksi yang Diketahui

  • Antihypertensive drugs (may enhance blood pressure lowering)
  • Stimulant medications (counteracts some stimulant side effects)
  • Sedative medications (additive calming effects)

Asupan atas yang dapat ditoleransi: 900 mg/day (no adverse effects observed in studies)

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Frequently Asked Questions

Does L-Theanine help with Sleep-Related Cognitive Impairment?
Based on 6 studies with 400 participants, there is limited but promising evidence that L-Theanine may support Sleep-Related Cognitive Impairment management. Our evidence grade is C (Some Evidence).
How much L-Theanine should I take for Sleep-Related Cognitive Impairment?
Studies have used various dosages. A commonly studied range is 100-200 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of L-Theanine?
Reported side effects may include Generally very well-tolerated, Mild drowsiness in sensitive individuals, Mild headache (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for L-Theanine and Sleep-Related Cognitive Impairment?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

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