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Magnesium L-Threonate untuk Sleep-Related Cognitive Impairment

C

Research suggests magnesium L-threonate may support sleep quality and sleep-dependent memory consolidation through NMDA receptor modulation in brain regions involved in sleep regulation.

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            C

        

        

            
Kesimpulan

            
            
Research suggests magnesium L-threonate may support sleep quality and sleep-dependent memory consolidation through NMDA receptor modulation in brain regions involved in sleep regulation.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Age-related memory decline via NR2B upregulation
                
                
                Efek: None
                
                
                None
                
            

            
            
Populasi: Elderly with age-related memory decline

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
4

        
Studi

    

    

        
300

        
Peserta

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Peringkat

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Expert opinion on …
                        2014
                        
                        55 sitasi
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosis yang Umum Digunakan

                

                    
                    

                        
general:

                        
1,500-2,000 mg/day (providing ~144 mg elemental magnesium)

                    

                    
                    

                        
cognitivesupport:

                        
2,000 mg/day

                    

                    
                

                
                

                    Batas atas: 350 mg/day elemental magnesium from supplements (IOM)
                

                
            

            

            
            

                
Dosis yang Diteliti dalam Penelitian

                

                    

                        
                            

                                Dosis
                                Durasi
                                Efek
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Waktu terbaik diminum: Evening preferred (may support sleep quality); split into 2-3 doses
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efek Samping yang Dilaporkan

                    
    
                        
                        
  • 
                            ⚠
                            Drowsiness
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild diarrhea
                        
    • 
                        
                    

                

                

                
                

                    
Interaksi yang Diketahui

                    
    
                        
                        
  • 
                            ●
                            Antibiotics (quinolones, tetracyclines — reduced absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Bisphosphonates (reduced absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Diuretics (may affect magnesium levels)
                        
    • 
                        
                        
  • 
                            ●
                            Muscle relaxants (additive sedation)
                        
    • 
                        
                    

                

                

                
                

                    

                        Asupan atas yang dapat ditoleransi: 350 mg/day elemental magnesium from supplements (IOM)
                    

                

                
            

            

                Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Magnesium L-Threonate help with Sleep-Related Cognitive Impairment?
            
        
        

            Based on 4 studies with 300 participants, there is limited but promising evidence that Magnesium L-Threonate may support Sleep-Related Cognitive Impairment management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Magnesium L-Threonate should I take for Sleep-Related Cognitive Impairment?
            
        
        

            Studies have used various dosages. A commonly studied range is 1,500-2,000 mg/day (providing ~144 mg elemental magnesium). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Magnesium L-Threonate?
            
        
        

            Reported side effects may include Drowsiness, Headache, Gastrointestinal discomfort, Mild diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Magnesium L-Threonate and Sleep-Related Cognitive Impairment?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Bahan lain untuk Sleep-Related Cognitive Impairment

                    

                        
                        
                            Melatonin
                            C

                        
                        
                        
                            Ashwagandha
                            C

                        
                        
                        
                            L-Theanine
                            C

                        
                        
                        
                            Creatine
                            C

                        
                        
                    

                

                

                
                

                    
Magnesium L-Threonate untuk kondisi lain

                    

                        
                        
                            Memory Loss
                            B

                        
                        
                    

                

                
            

        

        

    


    
    












    

        Penafian FDA:
        Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.