What is the recommended dosage for Blueberry Extract?

General: 500-1,000 mg/day extract (equivalent to 1-2 cups fresh blueberries)

What are the side effects of Blueberry Extract?

Potential side effects include: Generally very well-tolerated, Mild gastrointestinal discomfort (rare).

What is Blueberry Extract?

Blueberry extract is rich in anthocyanins, a class of flavonoid antioxidants that give blueberries their deep color. Research suggests these compounds may cross the blood-brain barrier and support brain health by reducing oxidative stress and inflammation in neural tissue.

What dosage of Blueberry Extract has been used in studies?

Cognitive studies have used the equivalent of approximately 1 to 2 cups of fresh blueberries daily, or 500 mg to 1,000 mg of concentrated extract standardized for anthocyanin content. Study durations have ranged from 6 to 24 weeks. Consult your healthcare provider.

What are the potential side effects of Blueberry Extract?

Blueberry extract is generally well tolerated with few reported side effects. Mild gastrointestinal discomfort is possible at high doses. Blueberries contain vitamin K, which may interact with blood-thinning medications. Consult your healthcare provider if you take anticoagulants.

Blueberry Extract

polyphenol

Also known as: Anthocyanin Extract, Vaccinium corymbosum Extract, Wild Blueberry Extract

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About

Blueberry anthocyanins cross the blood-brain barrier and accumulate in hippocampal and cortical regions. Multiple RCTs in older adults show memory improvements through CREB/BDNF pathway activation and reduced neuroinflammation.

How It Works

Anthocyanin polyphenols cross the BBB and accumulate in brain regions; activate CREB/BDNF signaling pathways; reduce neuroinflammation via NF-kB inhibition; enhance cerebral blood flow and neurovascular coupling.

Evidence For Conditions

Condition	Grade	Studies	Participants
Memory Loss	B	8	500	View →

Side Effects

Generally very well-tolerated
Mild gastrointestinal discomfort (rare)

Drug & Supplement Interactions

Anticoagulants (mild theoretical interaction)
Antidiabetic drugs (may enhance blood sugar lowering)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Green Tea Extract (EGCG)

Quick Facts

Dosage: General: 500-1,000 mg/day extract (equivalent to 1-2 cups fresh blueberries)
Forms: capsule powder
Natural Sources: Blueberries (wild > cultivated), Bilberries, Acai, Purple grapes
Upper Limit: Not established; food-derived, excellent safety profile
Best Time: With meals

Evidence Summary

Memory Loss B

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.