What is the recommended dosage for Green Tea Extract (EGCG)?

General: 250-500 mg/day EGCG; Via Tea: 3-5 cups/day

What are the side effects of Green Tea Extract (EGCG)?

Potential side effects include: Liver toxicity at high doses (>800 mg EGCG/day), Insomnia (caffeine content), Gastrointestinal discomfort, Iron absorption reduction.

What is Green Tea Extract?

Green tea extract is rich in polyphenols, particularly epigallocatechin gallate (EGCG), and contains L-theanine and small amounts of caffeine. These compounds have been studied for their potential neuroprotective, anti-inflammatory, and cognitive-enhancing effects.

What dosage of Green Tea Extract has been used in cognitive studies?

Cognitive studies have used 250 mg to 500 mg of green tea extract daily, typically standardized to contain 50% or more EGCG. Some studies have used higher doses. Decaffeinated versions are available for those sensitive to caffeine. Consult your healthcare provider.

What are the potential side effects of Green Tea Extract?

Green tea extract is generally safe at moderate doses. High doses of EGCG (above 800 mg) have been associated with liver toxicity in rare cases. Caffeine content may cause insomnia, anxiety, or digestive issues. Consult your healthcare provider, especially if you have liver conditions.

Green Tea Extract (EGCG)

polyphenol

Also known as: EGCG, Epigallocatechin Gallate, Camellia sinensis Extract

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About

EGCG (epigallocatechin gallate) crosses the blood-brain barrier, inhibits beta-amyloid aggregation, and provides antioxidant neuroprotection. Epidemiological data strongly associates regular green tea consumption with reduced cognitive decline risk.

How It Works

EGCG crosses the blood-brain barrier; inhibits beta-amyloid aggregation and tau phosphorylation; modulates dopaminergic and serotonergic pathways; enhances alpha brainwave activity.

Evidence For Conditions

Condition	Grade	Studies	Participants
Oxidative Stress & Neuroinflammation	C	10	800	View →

Side Effects

Liver toxicity at high doses (>800 mg EGCG/day)
Insomnia (caffeine content)
Gastrointestinal discomfort
Iron absorption reduction

Drug & Supplement Interactions

Iron supplements (tannins reduce absorption)
Nadolol (reduces blood levels)
Blood thinners (mild antiplatelet effect)
MAO inhibitors (caffeine interaction)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Blueberry Extract

Quick Facts

Dosage: General: 250-500 mg/day EGCG; Via_Tea: 3-5 cups/day
Forms: capsule tablet powder tea
Natural Sources: Green tea, Matcha, White tea
Upper Limit: 800 mg/day EGCG from supplements (hepatotoxicity risk above)
Best Time: Between meals; avoid on empty stomach

Evidence Summary

Oxidative Stress & Neuroinflammation C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.