What is the recommended dosage for Selenium?

General: 55 mcg/day (RDA); Cognitive Support: 100-200 mcg/day

What are the side effects of Selenium?

Potential side effects include: Garlic-like breath odor at high doses, Hair loss and nail brittleness (selenosis), Gastrointestinal discomfort, Fatigue.

Selenium is an essential trace mineral that supports antioxidant defense through selenoproteins such as glutathione peroxidase. The brain is vulnerable to oxidative damage, and adequate selenium status has been associated with better cognitive outcomes in observational studies, particularly in populations with low baseline selenium.

What dosage of Selenium has been used in cognitive studies?

The recommended dietary allowance for selenium is 55 mcg per day for adults. Cognitive studies have used 100 mcg to 200 mcg daily. Selenomethionine and selenium yeast are common supplemental forms. The tolerable upper intake is 400 mcg per day. Consult your healthcare provider.

What are the potential side effects of Selenium?

Chronic intake above 400 mcg per day may cause selenosis, characterized by garlic breath, hair loss, brittle nails, and neurological symptoms. Selenium has a narrow therapeutic window. Consult your healthcare provider and consider testing your selenium status before supplementing.

Selenium

mineral

Also known as: Selenomethionine, Sodium Selenite, Selenium Yeast

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About

Selenium is an essential component of selenoproteins that protect neurons from oxidative damage. Selenoprotein P is the brain's primary selenium transporter. Combined with NAC, it shows synergistic neuroprotective effects.

How It Works

Essential component of selenoproteins (glutathione peroxidases, thioredoxin reductases) protecting neurons from oxidative damage; supports thyroid hormone metabolism critical for brain function.

Side Effects

Garlic-like breath odor at high doses
Hair loss and nail brittleness (selenosis)
Gastrointestinal discomfort
Fatigue

Drug & Supplement Interactions

Statins (may reduce effectiveness)
Chemotherapy agents (may reduce efficacy)
Gold salts (reduced selenium levels)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Magnesium L-Threonate Zinc

Quick Facts

Dosage: General: 55 mcg/day (RDA); Cognitive_Support: 100-200 mcg/day
Forms: capsule tablet
Natural Sources: Brazil nuts, Tuna, Sardines, Eggs, Sunflower seeds
Upper Limit: 400 mcg/day (selenosis risk above)
Best Time: With meals

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.