What is the recommended dosage for Uridine Monophosphate?

General: 150-250 mg/day; Cognitive Support: 250-500 mg sublingually

What are the side effects of Uridine Monophosphate?

Potential side effects include: Mild gastrointestinal discomfort, Headache (rare), Nervousness at high doses.

What is Uridine Monophosphate?

Uridine monophosphate (UMP) is a nucleotide involved in RNA synthesis and phospholipid metabolism in the brain. It supports the production of CDP-choline and phosphatidylcholine, key components of neuronal membranes. Research has explored its potential to enhance synaptic function, especially when combined with omega-3 fatty acids and choline.

What dosage of Uridine Monophosphate has been used in studies?

Studies have used 150 mg to 1,000 mg of uridine monophosphate daily. It is often studied as part of multi-nutrient formulations including DHA and choline (the Fortasyn Connect formulation). Consult your healthcare provider for dosing recommendations.

What are the potential side effects of Uridine Monophosphate?

Uridine monophosphate is generally considered safe at recommended doses. Mild digestive discomfort has been reported. Long-term safety data from standalone supplementation is limited. Consult your healthcare provider before use, particularly if you are taking other medications.

Uridine Monophosphate

nootropic

Also known as: UMP, Uridine 5'-Monophosphate

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About

Uridine Monophosphate is a precursor to CDP-choline and phosphatidylcholine synthesis. It synergizes with DHA and choline sources (the 'Mr. Happy Stack') to support dopamine receptor expression and neuronal membrane phospholipid production.

How It Works

Precursor to CDP-choline and phosphatidylcholine synthesis; supports neuronal membrane production; enhances synaptic plasticity; synergizes with DHA and choline for dopamine receptor expression.

Evidence For Conditions

Condition	Grade	Studies	Participants
Neurotransmitter Imbalance	C	4	300	View →

Side Effects

Mild gastrointestinal discomfort
Headache (rare)
Nervousness at high doses

Drug & Supplement Interactions

No significant drug interactions established

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Citicoline Creatine Phosphatidylserine

Quick Facts

Dosage: General: 150-250 mg/day; Cognitive_Support: 250-500 mg sublingually
Forms: capsule powder sublingual tablet
Natural Sources: Broccoli, Tomatoes, Beer, Organ meats, Brewer's yeast
Upper Limit: Not established; well-tolerated up to 1,000 mg/day
Best Time: Morning; synergizes with DHA and choline sources

Evidence Summary

Neurotransmitter Imbalance C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.