Bacopa monnieri ： Age-Related Cognitive Decline
BA network meta-analysis found Bacopa outperformed Ginkgo on memory outcomes in elderly participants. Research suggests enhanced delayed word recall and improved Stroop Task performance with consistent supplementation.
結論
A network meta-analysis found Bacopa outperformed Ginkgo on memory outcomes in elderly participants. Research suggests enhanced delayed word recall and improved Stroop Task performance with consistent supplementation.
Key Study Findings
対象集団: elderly participants with MoCA score >=24
対象集団: patients with amnestic mild cognitive impairment, mean age 62.2 years, 88.3% men
対象集団: Rotenone-induced Parkinson's disease mouse model
対象集団: In vivo animal models of AD
対象集団: In silico AD modeling (systems biology)
対象集団: Healthy older adults
Key Statistics
15
研究数
1200
参加者数
Positive
グレード
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 300-600 mg/day standardized to 50% bacosides
- memorysupport:
- 300 mg/day for minimum 8-12 weeks
上限量： Not established; well-tolerated up to 600 mg/day in trials
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| 120 mL twice daily for 45 days | 6 weeks | Neutral | -- |
| 300 mg/day standardized Bacopa monnieri extract | 12 weeks | Neutral | 76 |
| 200 mg/kg body weight | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 1861 |
| None | -- | Mixed | -- |
| None | 12 weeks | Positive | -- |
推奨摂取タイミング： With meals; effects require 8-12 weeks of consistent use
Safety & Side Effects
報告されている副作用
- ⚠ Gastrointestinal discomfort (nausea, cramping, diarrhea)
- ⚠ Dry mouth
- ⚠ Fatigue in some individuals
- ⚠ Mild sedation at higher doses
既知の相互作用
- ● Thyroid medications (may increase thyroid hormone levels)
- ● Anticholinergic drugs (opposes cholinergic enhancement)
- ● Sedative medications (additive CNS depression)
- ● Calcium channel blockers (may enhance blood pressure lowering)
耐容上限摂取量： Not established; well-tolerated up to 600 mg/day in trials
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Bacopa monnieri help with Age-Related Cognitive Decline?
How much Bacopa monnieri should I take for Age-Related Cognitive Decline?
Are there side effects of Bacopa monnieri?
How strong is the evidence for Bacopa monnieri and Age-Related Cognitive Decline?
Related Evidence
に関する他の成分： Age-Related Cognitive Decline
Bacopa monnieri 他の症状・状態について
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