Gotu Kola 用于 Age-Related Cognitive Decline
DA traditional Ayurvedic brain tonic with emerging evidence for neuroprotective effects. Triterpene saponins promote nerve growth and dendritic arborization, but clinical evidence remains limited.
结论
A traditional Ayurvedic brain tonic with emerging evidence for neuroprotective effects. Triterpene saponins promote nerve growth and dendritic arborization, but clinical evidence remains limited.
Key Study Findings
研究人群: In vivo animal models of AD
研究人群: 18-month-old male and female C57BL6/J mice
研究人群: 3D intestinal model and neuronal/astrocytic co-culture
研究人群: Aged (18-month) C57BL6/J mice
研究人群: Patients with diabetes and Alzheimer's disease (review)
研究人群: In silico AD drug discovery (820 metabolites screened)
Key Statistics
4
研究数量
200
受试者
Positive
等级
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 500-1,000 mg/day standardized extract
- cognitivesupport:
- 750 mg/day
上限： Not established; hepatotoxicity reported rarely at very high doses
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| 1000 mg/kg/day | -- | Positive | -- |
| None | -- | Positive | -- |
| 1000 mg/kg/day | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 1 μg/mL | -- | Positive | -- |
最佳服用时间： With meals
Safety & Side Effects
已报告的副作用
- ⚠ Skin irritation (topical)
- ⚠ Headache
- ⚠ Gastrointestinal discomfort
- ⚠ Drowsiness
- ⚠ Rare: liver toxicity at very high doses
已知相互作用
- ● Hepatotoxic drugs (additive liver stress)
- ● Sedative medications (additive CNS depression)
- ● Cholesterol-lowering drugs (theoretical interaction)
可耐受最高摄入量： Not established; hepatotoxicity reported rarely at very high doses
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Gotu Kola help with Age-Related Cognitive Decline?
How much Gotu Kola should I take for Age-Related Cognitive Decline?
Are there side effects of Gotu Kola?
How strong is the evidence for Gotu Kola and Age-Related Cognitive Decline?
Related Evidence
其他成分用于 Age-Related Cognitive Decline
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