What is the recommended dosage for Ashwagandha?

General: 300-600 mg/day of root extract (KSM-66 or Sensoril); Cognitive Support: 600 mg/day

What are the side effects of Ashwagandha?

Potential side effects include: Drowsiness, Gastrointestinal discomfort, Rare: liver injury (with contaminated or high-dose products), Thyroid hormone elevation (may affect thyroid medications).

Ashwagandha (Withania somnifera) is an adaptogenic herb used in traditional Ayurvedic medicine. Modern research has investigated its potential to support cognitive function, reduce stress-related cognitive impairment, and promote healthy cortisol levels.

What dosage of Ashwagandha has been used in cognitive studies?

Clinical trials for cognitive outcomes have typically used 300 mg to 600 mg daily of standardized root extract (such as KSM-66 or Sensoril). Some studies have used up to 1,000 mg per day. Consult your healthcare provider for personalized dosing.

What are the potential side effects of Ashwagandha?

Ashwagandha is generally well tolerated in clinical trials. Possible side effects include mild gastrointestinal discomfort, drowsiness, and headache. It may interact with thyroid, sedative, and immunosuppressant medications. Pregnant or nursing women should avoid use.

Ashwagandha
Ashwagandha

herb

Aussi connu sous le nom de: Withania somnifera, Indian Ginseng, Winter Cherry, KSM-66, Sensoril

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About

Ashwagandha is the most scientifically supported adaptogen for cognitive and stress-related outcomes. Its withanolides reduce neuroinflammation, promote GABA-mimetic activity, and support neuronal regeneration. In a double-blind RCT, 240 mg/day for 60 days significantly reduced anxiety, with moderate improvements in attention, executive function, and information processing speed.

How It Works

Adaptogenic root that modulates the HPA axis to reduce cortisol levels; withanolides exhibit neuroprotective properties by reducing neuroinflammation, promoting GABA-mimetic activity, and supporting neuronal regeneration.

Evidence For Conditions

Pathologie	Note	Études	Participants
Stress-Induced Cognitive Decline	B	14	1200	Voir →
Anxiety-Related Cognitive Impairment	B	12	1000	Voir →
Sleep-Related Cognitive Impairment	C	6	500	Voir →

Side Effects

Drowsiness
Gastrointestinal discomfort
Rare: liver injury (with contaminated or high-dose products)
Thyroid hormone elevation (may affect thyroid medications)

Drug & Supplement Interactions

Thyroid medications (may increase thyroid hormone levels)
Sedative medications (additive CNS depression)
Immunosuppressants (may stimulate immune activity)
Diabetes medications (may lower blood sugar)

Informez toujours votre professionnel de santé de tous les compléments alimentaires que vous prenez.Informez toujours votre professionnel de santé de tous les compléments que vous prenez.

Related Ingredients

Rhodiola rosea Panax Ginseng Gotu Kola Bacopa monnieri Ginkgo biloba

En bref

Posologie: General: 300-600 mg/day of root extract (KSM-66 or Sensoril); Cognitive_Support: 600 mg/day
Formes: capsule powder liquid extract gummy
Sources naturelles: Withania somnifera root
Limite supérieure: Not established; well-tolerated up to 1,250 mg/day
Meilleur moment: With meals; morning or evening depending on individual response

Synthèse des preuves

Stress-Induced Cognitive Decline B

Anxiety-Related Cognitive Impairment B

Sleep-Related Cognitive Impairment C

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.