What is the recommended dosage for Ashwagandha?

General: 300-600 mg/day of root extract (KSM-66 or Sensoril); Cognitive Support: 600 mg/day

What are the side effects of Ashwagandha?

Potential side effects include: Drowsiness, Gastrointestinal discomfort, Rare: liver injury (with contaminated or high-dose products), Thyroid hormone elevation (may affect thyroid medications).

Ashwagandha (Withania somnifera) is an adaptogenic herb used in traditional Ayurvedic medicine. Modern research has investigated its potential to support cognitive function, reduce stress-related cognitive impairment, and promote healthy cortisol levels.

What dosage of Ashwagandha has been used in cognitive studies?

Clinical trials for cognitive outcomes have typically used 300 mg to 600 mg daily of standardized root extract (such as KSM-66 or Sensoril). Some studies have used up to 1,000 mg per day. Consult your healthcare provider for personalized dosing.

What are the potential side effects of Ashwagandha?

Ashwagandha is generally well tolerated in clinical trials. Possible side effects include mild gastrointestinal discomfort, drowsiness, and headache. It may interact with thyroid, sedative, and immunosuppressant medications. Pregnant or nursing women should avoid use.

Ashwagandha
Ashwagandha

herb

También conocido como: Withania somnifera, Indian Ginseng, Winter Cherry, KSM-66, Sensoril

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About

Ashwagandha is the most scientifically supported adaptogen for cognitive and stress-related outcomes. Its withanolides reduce neuroinflammation, promote GABA-mimetic activity, and support neuronal regeneration. In a double-blind RCT, 240 mg/day for 60 days significantly reduced anxiety, with moderate improvements in attention, executive function, and information processing speed.

How It Works

Adaptogenic root that modulates the HPA axis to reduce cortisol levels; withanolides exhibit neuroprotective properties by reducing neuroinflammation, promoting GABA-mimetic activity, and supporting neuronal regeneration.

Evidence For Conditions

Condición	Calificación	Estudios	Participantes
Stress-Induced Cognitive Decline	B	14	1200	Ver →
Anxiety-Related Cognitive Impairment	B	12	1000	Ver →
Sleep-Related Cognitive Impairment	C	6	500	Ver →

Side Effects

Drowsiness
Gastrointestinal discomfort
Rare: liver injury (with contaminated or high-dose products)
Thyroid hormone elevation (may affect thyroid medications)

Drug & Supplement Interactions

Thyroid medications (may increase thyroid hormone levels)
Sedative medications (additive CNS depression)
Immunosuppressants (may stimulate immune activity)
Diabetes medications (may lower blood sugar)

Informe siempre a su profesional de salud sobre todos los suplementos que toma.Siempre informe a su profesional de salud sobre todos los suplementos que toma.

Rhodiola rosea Panax Ginseng Ginkgo biloba Bacopa monnieri Gotu Kola

Datos rápidos

Dosificación: General: 300-600 mg/day of root extract (KSM-66 or Sensoril); Cognitive_Support: 600 mg/day
Formas: capsule powder liquid extract gummy
Fuentes naturales: Withania somnifera root
Límite superior: Not established; well-tolerated up to 1,250 mg/day
Mejor momento: With meals; morning or evening depending on individual response

Resumen de evidencia

Stress-Induced Cognitive Decline B

Anxiety-Related Cognitive Impairment B

Sleep-Related Cognitive Impairment C

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.