Skip to main content
BrainCited

Taurine untuk Oxidative Stress & Neuroinflammation

C

Research suggests taurine's anti-excitotoxic effects and neuronal calcium homeostasis support may help protect against oxidative neuronal damage. Preclinical evidence is strong; human cognitive trials are limited.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'braincited.com'; const params = 'ingredient\u003Dtaurine\u0026condition\u003Doxidative\u002Dneuroinflammation'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

C

Kesimpulan

Research suggests taurine's anti-excitotoxic effects and neuronal calcium homeostasis support may help protect against oxidative neuronal damage. Preclinical evidence is strong; human cognitive trials are limited.

Key Study Findings

Review
Taurine as an Early-Phase Disease-Modifying Candidate for Alzheimer's Disease.
Dose: None vs: None Outcome: None Efek: None None

Populasi: narrative review of taurine neuroprotective actions in Alzheimer's disease

Other
Ultramicronized palmitoylethanolamide restores astrocyte-neuron metabolic coupling and Klotho/FGF21 signaling in a triple-transgenic mouse model of …
Dose: None vs: untreated 3xTg-AD mice Outcome: metabolic coupling restoration (lactate-glutamate dynamics, taurine metabolism) Efek: None None

Populasi: 6- and 12-month-old triple transgenic (3xTg-AD) Alzheimer's disease mice

Controlled Clinical Trial 6 weeks
Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac …
Dose: 400 mg/kg/day vs: ROFA exposure without taurine Outcome: Multi-organ oxidative stress and neuroinflammation Efek: None None

Populasi: Male Wistar rats with intranasal ROFA exposure

Other n=70
Synergetic effect of taurine/taurine nanoparticles along with Sinemet® against rotenone-induced Parkinson's disease in mice.
Dose: None vs: Rotenone-induced PD model controls Outcome: Neuroprotection in rotenone-induced PD mice Efek: None None

Populasi: Rotenone-induced Parkinson's disease mice (10 groups)

Other
Taurine ameliorates viral encephalitis by restoring PRKN-mediated mitophagy.
Dose: None vs: HSV-1 infected cells/mice without taurine Outcome: HSV-1 infection and viral encephalitis severity Efek: None None

Populasi: HSV-1 viral encephalitis in vitro and mouse model

Other 4 weeks
Taurine suppresses Aβ aggregation and attenuates Alzheimer's disease pathologies in 5XFAD mice and patient-derived cerebral …
Dose: 1000 mg/kg oral for 4 weeks vs: Vehicle control in 5XFAD mice Outcome: Aβ accumulation, tau phosphorylation, neuroinflammation Efek: None None

Populasi: 5XFAD AD mice and patient-derived cerebral organoids

Key Statistics

6

Studi

300

Peserta

Positive

C

Peringkat

Referenced Papers

NPJ Parkinson's disease 2024 57 sitasi
Frontiers in bioscience … 2015 62 sitasi
British journal of … 2014 111 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
500-2,000 mg/day
cognitivesupport:
1,000-3,000 mg/day

Batas atas: 3,000 mg/day (EFSA safety assessment)

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
None -- Positive --
None -- Positive --
400 mg/kg/day 6 weeks Mixed --
None -- Positive 70
None -- Positive --
1000 mg/kg oral for 4 weeks 4 weeks Positive --
None -- Mixed --
None -- Mixed --

Waktu terbaik diminum: With or without food; may be calming if taken evening

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Generally very well-tolerated
  • Mild gastrointestinal discomfort (rare)
  • Drowsiness at high doses

Interaksi yang Diketahui

  • Antihypertensive drugs (additive blood pressure lowering)
  • Antiepileptic drugs (may enhance GABA effects)

Asupan atas yang dapat ditoleransi: 3,000 mg/day (EFSA safety assessment)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Taurine help with Oxidative Stress & Neuroinflammation?
Based on 6 studies with 300 participants, there is limited but promising evidence that Taurine may support Oxidative Stress & Neuroinflammation management. Our evidence grade is C (Some Evidence).
How much Taurine should I take for Oxidative Stress & Neuroinflammation?
Studies have used various dosages. A commonly studied range is 500-2,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Taurine?
Reported side effects may include Generally very well-tolerated, Mild gastrointestinal discomfort (rare), Drowsiness at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Taurine and Oxidative Stress & Neuroinflammation?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

Related Evidence

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.