Taurine 관련 산화 스트레스 및 신경염증
C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.Research suggests taurine's anti-excitotoxic effects and neuronal calcium homeostasis support may help protect against oxidative neuronal damage. Preclinical evidence is strong; human cognitive trials are limited.
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C
결론
Research suggests taurine's anti-excitotoxic effects and neuronal calcium homeostasis support may help protect against oxidative neuronal damage. Preclinical evidence is strong; human cognitive trials are limited.
Key Study Findings
Review
Taurine as an Early-Phase Disease-Modifying Candidate for Alzheimer's Disease.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: narrative review of taurine neuroprotective actions in Alzheimer's disease
Other
Ultramicronized palmitoylethanolamide restores astrocyte-neuron metabolic coupling and Klotho/FGF21 signaling in a triple-transgenic mouse model of …
Dose: None
vs: untreated 3xTg-AD mice
Outcome: metabolic coupling restoration (lactate-glutamate dynamics, taurine metabolism)
효과: None
None
대상 집단: 6- and 12-month-old triple transgenic (3xTg-AD) Alzheimer's disease mice
Controlled Clinical Trial
6 weeks
Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac …
Dose: 400 mg/kg/day
vs: ROFA exposure without taurine
Outcome: Multi-organ oxidative stress and neuroinflammation
효과: None
None
대상 집단: Male Wistar rats with intranasal ROFA exposure
Other
n=70
Synergetic effect of taurine/taurine nanoparticles along with Sinemet® against rotenone-induced Parkinson's disease in mice.
Dose: None
vs: Rotenone-induced PD model controls
Outcome: Neuroprotection in rotenone-induced PD mice
효과: None
None
대상 집단: Rotenone-induced Parkinson's disease mice (10 groups)
Other
Taurine ameliorates viral encephalitis by restoring PRKN-mediated mitophagy.
Dose: None
vs: HSV-1 infected cells/mice without taurine
Outcome: HSV-1 infection and viral encephalitis severity
효과: None
None
대상 집단: HSV-1 viral encephalitis in vitro and mouse model
Other
4 weeks
Taurine suppresses Aβ aggregation and attenuates Alzheimer's disease pathologies in 5XFAD mice and patient-derived cerebral …
Dose: 1000 mg/kg oral for 4 weeks
vs: Vehicle control in 5XFAD mice
Outcome: Aβ accumulation, tau phosphorylation, neuroinflammation
효과: None
None
대상 집단: 5XFAD AD mice and patient-derived cerebral organoids
Key Statistics
6
연구
300
참여자
↑
Positive
C
등급
Referenced Papers
International journal of …
2026
Biomedicine & pharmacotherapy …
2026
Journal of advanced …
2025
13 인용
Metabolic brain disease
2025
10 인용
Metabolic brain disease
2025
7 인용
Frontiers in nutrition
2025
7 인용
Asian Pacific journal …
2025
6 인용
Inflammation
2025
6 인용
Autophagy
2025
4 인용
Phytomedicine : international …
2025
3 인용
Biomedicine & pharmacotherapy …
2025
2 인용
Archives of pharmacal …
2025
1 인용
Toxicology mechanisms and …
2025
1 인용
Psychoneuroendocrinology
2025
1 인용
Research square
2025
The Journal of …
2025
Toxicology research
2025
Neurotoxicology
2025
NPJ Parkinson's disease
2024
57 인용
Journal of neuroinflammation
2024
42 인용
Molecular and cellular …
2024
13 인용
Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.
Other
PloS one
2024
5 인용
Protective effects of taurine on heat Stress-Induced cognitive impairment through Npas4 and Lcn2.
Other
International immunopharmacology
2024
4 인용
Frontiers in medicine
2024
4 인용
Aging
2024
2 인용
Frontiers in aging
2023
76 인용
Food & function
2023
15 인용
BMC geriatrics
2023
12 인용
Chemistry & biodiversity
2023
6 인용
Frontiers in endocrinology
2022
52 인용
Scientific reports
2022
31 인용
Toxicological sciences : …
2022
29 인용
Journal of immunology …
2021
20 인용
GeroScience
2021
9 인용
Human gene therapy
2020
32 인용
Biomolecules
2020
28 인용
Life sciences
2019
110 인용
Amino acids
2018
50 인용
Journal of neurochemistry
2018
30 인용
Amino acids
2018
23 인용
Neurochemistry international
2017
56 인용
Alcohol (Fayetteville, N.Y.)
2015
122 인용
Frontiers in bioscience …
2015
62 인용
British journal of …
2014
111 인용
Food and chemical …
2014
102 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 500-2,000 mg/day
- cognitivesupport:
- 1,000-3,000 mg/day
상한량: 3,000 mg/day (EFSA safety assessment)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 400 mg/kg/day | 6 weeks | Mixed | -- |
| None | -- | Positive | 70 |
| None | -- | Positive | -- |
| 1000 mg/kg oral for 4 weeks | 4 weeks | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
권장 복용 시간: With or without food; may be calming if taken evening
Safety & Side Effects
보고된 부작용
- ⚠ Generally very well-tolerated
- ⚠ Mild gastrointestinal discomfort (rare)
- ⚠ Drowsiness at high doses
알려진 상호작용
- ● Antihypertensive drugs (additive blood pressure lowering)
- ● Antiepileptic drugs (may enhance GABA effects)
일일 최대 섭취 허용량: 3,000 mg/day (EFSA safety assessment)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Taurine help with 산화 스트레스 및 신경염증?
Based on 6 studies with 300 participants, there is limited but promising evidence that Taurine may support 산화 스트레스 및 신경염증 management. Our evidence grade is C (Some Evidence).
How much Taurine should I take for 산화 스트레스 및 신경염증?
Studies have used various dosages. A commonly studied range is 500-2,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Taurine?
Reported side effects may include Generally very well-tolerated, Mild gastrointestinal discomfort (rare), Drowsiness at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Taurine and 산화 스트레스 및 신경염증?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 산화 스트레스 및 신경염증
References
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FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.