N-Acetyl Cysteine 관련 산화 스트레스 및 신경염증
B 근거 적어도 하나의 무작위 시험이 이를 지지하며, 대체로 일관된 결과를 보입니다.As a glutathione precursor, NAC provides potent antioxidant and anti-inflammatory neuroprotection. Combined with selenium, research suggests synergistic protection against oxidative brain injury.
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B
결론
As a glutathione precursor, NAC provides potent antioxidant and anti-inflammatory neuroprotection. Combined with selenium, research suggests synergistic protection against oxidative brain injury.
Key Study Findings
Other
Executive Summary of the Vulvodynia Therapeutic Research Summit.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: expert consensus on therapeutics for provoked vestibulodynia
In Vitro
Neuroinflammation-Modulating Properties Combining Glutathione, N-Acetylcysteine, and Uridine Monophosphate in a Formulation Supplement: An In Vitro …
Dose: None
vs: ALA-based formula (SUPERALA CARNITINE)
Outcome: Neuroprotective and anti-inflammatory effects
효과: None
None
대상 집단: 3D in vitro gut-peripheral nerve axis model
Review
Combination Supplement Therapy: A New Frontier in Treatment of Neurodegenerative Diseases.
Dose: None
vs: None
Outcome: Neurodegenerative disease pathology attenuation
효과: None
None
대상 집단: Preclinical neurodegenerative disease models
Systematic Review
Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications.
Dose: None
vs: None
Outcome: Antidepressant effects (neurotransmitter modulation)
효과: None
None
대상 집단: Preclinical models
Review
Noise exposure-induced the cerebral alterations: From emerging evidence to antioxidant-mediated prevention and treatment.
Dose: None
vs: None
Outcome: Inflammatory markers
효과: None
None
대상 집단: Depression patients
Review
Underlying Mechanisms of Brain Aging and Neurodegenerative Diseases as Potential Targets for Preventive or Therapeutic …
Dose: Various phytochemicals
vs: None
Outcome: Neuroprotection in aging and neurodegeneration
효과: None
None
대상 집단: Aging brain and NDD models (review)
Key Statistics
12
연구
800
참여자
↑
Positive
B
등급
Referenced Papers
Obstetrics and gynecology
2026
Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications.
Systematic Review
Molecular nutrition & …
2025
8 인용
Brain sciences
2025
The Journal of …
2025
Ecotoxicology and environmental …
2024
7 인용
Nutrients
2023
31 인용
The journal of …
2021
41 인용
Journal of fungi …
2021
14 인용
Sleep medicine clinics
2021
14 인용
Biomolecules
2020
28 인용
Neuroscience and biobehavioral …
2019
45 인용
N-acetyl-l-cysteine attenuates oxidative damage and neurodegeneration in rat brain during aging.
Other
Canadian journal of …
2018
37 인용
Medical hypotheses
2014
36 인용
Restless legs syndrome.
Review
Handbook of clinical …
2011
8 인용
Brain research. Molecular …
2005
160 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 600-1,800 mg/day
- neuroprotection:
- 1,200-2,400 mg/day
상한량: Not established as supplement; 6,000+ mg/day used clinically (IV)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| Various phytochemicals | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
권장 복용 시간: On empty stomach; split into 2-3 doses; supplement zinc if using long-term
Safety & Side Effects
보고된 부작용
- ⚠ Nausea and vomiting
- ⚠ Diarrhea
- ⚠ Unpleasant sulfur taste/smell
- ⚠ Rare: bronchospasm (inhaled form)
- ⚠ Long-term use may deplete zinc stores
알려진 상호작용
- ● Nitroglycerin (may enhance hypotensive effects)
- ● Activated charcoal (reduces NAC absorption)
- ● Anticoagulants (theoretical interaction)
일일 최대 섭취 허용량: Not established as supplement; 6,000+ mg/day used clinically (IV)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does N-Acetyl Cysteine help with 산화 스트레스 및 신경염증?
Based on 12 studies with 800 participants, there is moderate evidence from clinical studies that N-Acetyl Cysteine may support 산화 스트레스 및 신경염증 management. Our evidence grade is B (Good Evidence).
How much N-Acetyl Cysteine should I take for 산화 스트레스 및 신경염증?
Studies have used various dosages. A commonly studied range is 600-1,800 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of N-Acetyl Cysteine?
Reported side effects may include Nausea and vomiting, Diarrhea, Unpleasant sulfur taste/smell, Rare: bronchospasm (inhaled form). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for N-Acetyl Cysteine and 산화 스트레스 및 신경염증?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 산화 스트레스 및 신경염증
N-Acetyl Cysteine 다른 건강 상태에 대한 근거
References
- [1] Jill M Krapf et al.. Obstet Gynecol. 2026. Executive Summary of the Vulvodynia Therapeutic Research Summit. doi:10.1097/AOG.0000000000006118 PubMed
- [2] Pin Gong et al.. Mol Nutr Food Res. 2025. Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional Implications. doi:10.1002/mnfr.70080 PubMed
- [3] Simone Mulè et al.. Brain Sci. 2025. Neuroinflammation-Modulating Properties Combining Glutathione, N-Acetylcysteine, and Uridine Monophosphate in a Formulation Supplement: An In Vitro Study. doi:10.3390/brainsci15121340 PubMed
- [4] Alexander Shtilbans. J Nutr. 2025. Combination Supplement Therapy: A New Frontier in Treatment of Neurodegenerative Diseases. doi:10.1016/j.tjnut.2025.07.004 PubMed
- [5] Yuyan Chen et al.. Ecotoxicol Environ Saf. 2024. Noise exposure-induced the cerebral alterations: From emerging evidence to antioxidant-mediated prevention and treatment. doi:10.1016/j.ecoenv.2024.117411 PubMed
- [6] Hamid Mostafavi Abdolmaleky et al.. Nutrients. 2023. Underlying Mechanisms of Brain Aging and Neurodegenerative Diseases as Potential Targets for Preventive or Therapeutic Strategies Using Phytochemicals. doi:10.3390/nu15153456 PubMed
- [7] Jonathan Paulo Agnes et al.. J Pain. 2021. Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation. doi:10.1016/j.jpain.2021.03.142 PubMed
- [8] Mihai-Vlad Valu et al.. J Fungi (Basel). 2021. Hericium erinaceus (Bull.) Pers. Ethanolic Extract with Antioxidant Properties on Scopolamine-Induced Memory Deficits in a Zebrafish Model of Cognitive Impairment. doi:10.3390/jof7060477 PubMed
- [9] Sergi Ferré et al.. Sleep Med Clin. 2021. Akathisia and Restless Legs Syndrome: Solving the Dopaminergic Paradox. doi:10.1016/j.jsmc.2021.02.012 PubMed
- [10] Mujtaba Aamir Bhat et al.. Biomolecules. 2020. Expedition into Taurine Biology: Structural Insights and Therapeutic Perspective of Taurine in Neurodegenerative Diseases. doi:10.3390/biom10060863 PubMed
- [11] Marc J Kaufman et al.. Neurosci Biobehav Rev. 2019. Supraphysiologic-dose anabolic-androgenic steroid use: A risk factor for dementia? doi:10.1016/j.neubiorev.2019.02.014 PubMed
- [12] Geetika Garg et al.. Can J Physiol Pharmacol. 2018. N-acetyl-l-cysteine attenuates oxidative damage and neurodegeneration in rat brain during aging. doi:10.1139/cjpp-2018-0209 PubMed
- [13] Alan D Strickland. Med Hypotheses. 2014. Prevention of cerebral palsy, autism spectrum disorder, and attention deficit-hyperactivity disorder. doi:10.1016/j.mehy.2014.02.003 PubMed
- [14] Lynn Marie Trotti et al.. Handb Clin Neurol. 2011. Restless legs syndrome. doi:10.1016/B978-0-444-52014-2.00047-1 PubMed
- [15] Birgit M Dietz et al.. Brain Res Mol Brain Res. 2005. Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro. doi:10.1016/j.molbrainres.2005.04.009 PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.