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Creatine 用于 记忆力减退

C 证据 来自小型研究的证据有限，但存在一些积极信号。

Research suggests moderate certainty evidence for positive effects on memory function. A pilot study in Alzheimer's patients indicated moderate cognitive improvements with creatine supplementation.

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            C

        

        

            
结论

            
            
Research suggests moderate certainty evidence for positive effects on memory function. A pilot study in Alzheimer's patients indicated moderate cognitive improvements with creatine supplementation.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Systematic Review
                
                
                
                
            

            
                Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Bone, muscle, and cognitive health in elderly
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Older adults

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                A review of creatine supplementation in age-related diseases: more than a supplement for athletes.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: men

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
10

        
研究数量

    

    

        
700

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        The journal of …
                        2017
                        
                        75 次引用
                        
                    

                

                
                

                    

                        
                            A review of creatine supplementation in age-related diseases: more than a supplement for athletes.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        F1000Research
                        2014
                        
                        84 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
3-5 g/day creatine monohydrate

                    

                    
                    

                        
cognitivesupport:

                        
5 g/day

                    

                    
                

                
                

                    上限： 5 g/day considered safe for long-term use (ISSN position)
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： Any time of day; with or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Water retention
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Weight gain (water weight)
                        
    • 
                        
                        
  • 
                            ⚠
                            Muscle cramping (rare, dose-dependent)
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Nephrotoxic drugs (monitor kidney function with concurrent use)
                        
    • 
                        
                        
  • 
                            ●
                            Caffeine (may partially attenuate creatine loading, debated)
                        
    • 
                        
                        
  • 
                            ●
                            NSAIDs (theoretical additive kidney stress at high doses)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： 5 g/day considered safe for long-term use (ISSN position)
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Creatine help with 记忆力减退?
            
        
        

            Based on 10 studies with 700 participants, there is limited but promising evidence that Creatine may support 记忆力减退 management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Creatine should I take for 记忆力减退?
            
        
        

            Studies have used various dosages. A commonly studied range is 3-5 g/day creatine monohydrate. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Creatine?
            
        
        

            Reported side effects may include Water retention, Mild gastrointestinal discomfort, Weight gain (water weight), Muscle cramping (rare, dose-dependent). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Creatine and 记忆力减退?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 10 peer-reviewed studies with 700 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Creatine 用于其他健康状况

                    

                        
                        
                            精神疲劳
                            B

                        
                        
                        
                            睡眠相关认知障碍
                            C

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      G Iolascon et al..
      J Nutr Health Aging.
      2017.
      Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
      doi:10.1007/s12603-016-0823-x
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Rachel N Smith et al..
      F1000Res.
      2014.
      A review of creatine supplementation in age-related diseases: more than a supplement for athletes.
      doi:10.12688/f1000research.5218.1
      PubMed
    
    3. 
    
  















    

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