What is the recommended dosage for Phosphatidylserine?

General: 100 mg/day; Cognitive Support: 100-300 mg/day

What are the side effects of Phosphatidylserine?

Potential side effects include: Mild gastrointestinal discomfort, Insomnia at high doses, Rare allergic reactions (soy-derived forms).

What is Phosphatidylserine?

Phosphatidylserine (PS) is a phospholipid that is a key component of brain cell membranes. It supports cell-to-cell communication and is involved in neurotransmitter release. Research has explored its potential to support memory, attention, and processing speed, particularly in aging populations.

What dosage of Phosphatidylserine has been used in studies?

Clinical trials have commonly used 100 mg to 300 mg of phosphatidylserine daily, often divided into three doses of 100 mg. Most modern supplements use soy- or sunflower-derived PS. Cognitive benefits have been observed over 6 to 12 weeks. Consult your healthcare provider.

What are the potential side effects of Phosphatidylserine?

Phosphatidylserine is generally well tolerated. Mild side effects may include digestive upset and insomnia at higher doses. It may interact with blood-thinning and anti-inflammatory medications. People with soy allergies should choose sunflower-derived PS. Consult your healthcare provider.

Phosphatidylserine

nootropic

Also known as: PS, Ptd-L-Ser, Soy Phosphatidylserine, Sunflower Phosphatidylserine

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'braincited.com'; const params = 'ingredient\u003Dphosphatidylserine'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

About

Phosphatidylserine is an essential phospholipid component of neuronal cell membranes that supports cell-to-cell communication and neurotransmitter release. The FDA has granted a qualified health claim stating it may reduce the risk of cognitive dysfunction in the elderly. Studies show modest improvements in memory, learning, and mood in older adults.

How It Works

Essential phospholipid component of neuronal cell membranes; supports cell-to-cell communication, neurotransmitter release (acetylcholine, dopamine), and cortisol regulation; maintains membrane fluidity critical for signal transduction.

Evidence For Conditions

Condition	Grade	Studies	Participants
Age-Related Cognitive Decline	B	16	1100	View →
Stress-Induced Cognitive Decline	C	6	400	View →
Attention & Focus Difficulties	C	5	350	View →

Side Effects

Mild gastrointestinal discomfort
Insomnia at high doses
Rare allergic reactions (soy-derived forms)

Drug & Supplement Interactions

Anticholinergic medications (may reduce PS effectiveness)
Blood thinners (theoretical interaction)
Cholinesterase inhibitors (additive cholinergic effects)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Citicoline Creatine Uridine Monophosphate

Quick Facts

Dosage: General: 100 mg/day; Cognitive_Support: 100-300 mg/day
Forms: softgel capsule
Natural Sources: Soybeans, Sunflower lecithin, White beans, Eggs
Upper Limit: Well-tolerated up to 600 mg/day
Best Time: With meals for better absorption

Evidence Summary

Age-Related Cognitive Decline B

Stress-Induced Cognitive Decline C

Attention & Focus Difficulties C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.