Rhodiola rosea для Mental Fatigue

Q: Does Rhodiola rosea help with Mental Fatigue?

Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).

Q: How much Rhodiola rosea should I take for Mental Fatigue?

Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Rhodiola rosea?

Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Rhodiola rosea and Mental Fatigue?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Multiple RCTs demonstrate significant reduction in mental fatigue and improved concentration during stressful periods. Rosavin and salidroside appear to be the primary active compounds supporting cognitive endurance.

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Итог

Key Study Findings

Randomized Controlled Trial n=18 Double-blind

The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises …

Dose: 4 days supplementation или: Placebo Outcome: Strength performance in bench-press and bench-pull Эффект: 17 small ESs observed, 14 favoring RR None

Популяция: Young healthy individuals (7 women, 11 men)

Review

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on …

Dose: None или: None Outcome: Inflammatory markers Эффект: None None

Популяция: Depression patients

Randomized Controlled Trial 4.3 weeks Single-blind

Assessing brain function in stressed healthy individuals following the use of a combination of green …

Dose: None или: placebo Outcome: Brain response to stress and quality of life Эффект: None p = 0.001

Популяция: Chronically stressed but healthy subjects

Review

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review.

Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Other 4 weeks

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance …

Dose: None или: Control group Outcome: acute and chronic effects of resistance exercise coupled … Эффект: None p < 0.05

Популяция: None

Review

Adaptogens in mental and behavioral disorders.

Dose: None или: None Outcome: Stress-protective and stimulative effects Эффект: None None

Популяция: Adults with mental and behavioral disorders

Key Statistics

Исследования

900

Участники

↑

Positive

Оценка

Referenced Papers

The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue … RCT

Nutrients 2025 6 цитирований

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea. Review

Journal of neural … 2024 8 цитирований

Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B … Other

Frontiers in nutrition 2023 3 цитирований

The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review. Review

Journal of clinical … 2021 38 цитирований

Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis … Other

Journal of the … 2020 25 цитирований

Adaptogens in mental and behavioral disorders. Review

The Psychiatric clinics … 2013 64 цитирований

Rhodiola rosea for physical and mental fatigue: a systematic review. Systematic Review

BMC complementary and … 2012 114 цитирований

Does Rhodiola rosea possess ergogenic properties? Review

International journal of … 2006 40 цитирований

[Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine]. Review

Medicina (Kaunas, Lithuania) 2004

A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for … RCT

Phytomedicine : international … 2003 205 цитирований

Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen … RCT

Phytomedicine : international … 2000 281 цитирований

A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of … RCT

Phytomedicine : international … 2000 251 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:: 200-600 mg/day standardized to 3% rosavins and 1% salidroside

Верхний предел: Not established; doses up to 680 mg/day used in trials

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
4 days supplementation	--	Positive	18
None	--	Mixed	--
None	4.3 weeks	Positive	--
None	--	Mixed	--
None	4 weeks	Mixed	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	--

Лучшее время приёма: Morning on empty stomach; avoid evening (may be stimulating)

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Insomnia or overstimulation (if taken late)
⚠ Dry mouth
⚠ Dizziness
⚠ Mild agitation

Известные взаимодействия

● Antidepressants (SSRIs, MAOIs — additive serotonergic effects)
● Antidiabetic drugs (may lower blood sugar)
● Stimulant medications (additive stimulatory effects)
● Immunosuppressants (may modulate immune response)

Допустимый верхний уровень потребления: Not established; doses up to 680 mg/day used in trials

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Rhodiola rosea help with Mental Fatigue?

Based on 11 studies with 900 participants, there is moderate evidence from clinical studies that Rhodiola rosea may support Mental Fatigue management. Our evidence grade is B (Good Evidence).

How much Rhodiola rosea should I take for Mental Fatigue?

Studies have used various dosages. A commonly studied range is 200-600 mg/day standardized to 3% rosavins and 1% salidroside. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Rhodiola rosea?

Reported side effects may include Insomnia or overstimulation (if taken late), Dry mouth, Dizziness, Mild agitation. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Rhodiola rosea and Mental Fatigue?

We rate the evidence as Grade B (Good Evidence). This rating is based on 11 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Mental Fatigue

Creatine B Panax Ginseng C

Rhodiola rosea для других состояний

Stress-Induced Cognitive Decline B

Краткий вывод

Evidence Strength72%

High confidence

Разбор исследований

RCT (4)Meta (0)Other (7)

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