Bacopa monnieri 用于 Age-Related Cognitive Decline
BA network meta-analysis found Bacopa outperformed Ginkgo on memory outcomes in elderly participants. Research suggests enhanced delayed word recall and improved Stroop Task performance with consistent supplementation.
结论
A network meta-analysis found Bacopa outperformed Ginkgo on memory outcomes in elderly participants. Research suggests enhanced delayed word recall and improved Stroop Task performance with consistent supplementation.
Key Study Findings
研究人群: elderly participants with MoCA score >=24
研究人群: patients with amnestic mild cognitive impairment, mean age 62.2 years, 88.3% men
研究人群: Rotenone-induced Parkinson's disease mouse model
研究人群: In vivo animal models of AD
研究人群: In silico AD modeling (systems biology)
研究人群: Healthy older adults
Key Statistics
15
研究数量
1200
受试者
Positive
等级
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 300-600 mg/day standardized to 50% bacosides
- memorysupport:
- 300 mg/day for minimum 8-12 weeks
上限： Not established; well-tolerated up to 600 mg/day in trials
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| 120 mL twice daily for 45 days | 6 weeks | Neutral | -- |
| 300 mg/day standardized Bacopa monnieri extract | 12 weeks | Neutral | 76 |
| 200 mg/kg body weight | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 1861 |
| None | -- | Mixed | -- |
| None | 12 weeks | Positive | -- |
最佳服用时间： With meals; effects require 8-12 weeks of consistent use
Safety & Side Effects
已报告的副作用
- ⚠ Gastrointestinal discomfort (nausea, cramping, diarrhea)
- ⚠ Dry mouth
- ⚠ Fatigue in some individuals
- ⚠ Mild sedation at higher doses
已知相互作用
- ● Thyroid medications (may increase thyroid hormone levels)
- ● Anticholinergic drugs (opposes cholinergic enhancement)
- ● Sedative medications (additive CNS depression)
- ● Calcium channel blockers (may enhance blood pressure lowering)
可耐受最高摄入量： Not established; well-tolerated up to 600 mg/day in trials
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Bacopa monnieri help with Age-Related Cognitive Decline?
How much Bacopa monnieri should I take for Age-Related Cognitive Decline?
Are there side effects of Bacopa monnieri?
How strong is the evidence for Bacopa monnieri and Age-Related Cognitive Decline?
Related Evidence
其他成分用于 Age-Related Cognitive Decline
Bacopa monnieri 用于其他健康状况
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